Fig. 3

EA intervention attenuated NLRP3 inflammasome activation in ankle joints of gout arthritis model mice. A–E Western blotting examination of protein expressions of NLRP3 inflammasome signaling components, including NLRP3 (A), Caspase-1 (B) ASC (C) and inflammatory cytokines IL-1β (D), IL-18 (E) in ankle joint tissues from control, MSU, MSU + EA and MSU + sham EA groups of mice. Upper panels showed the representative Western blot gels, whereas lower panels indicated the summarized data. n = 5–6 mice/group. *p < 0.05. NS no significance