Table 3 LC–MS measurement parameters of differentially expressed serum components in TBHLD
No | Name | mz | rt/s | ppm | log2FC | p.value | VIP | Type |
|---|---|---|---|---|---|---|---|---|
1 | 5-Hydroxypentanoic acid | 119.073 | 201.6 | 22.87672 | − 0.45 | 0.008342 | 1.683273 | pos |
2 | L-Leucine | 132.1019 | 80.8 | 0.181678 | 0.31 | 0.012864 | 1.66091 | pos |
3 | 5,6-Dihydro-5-fluorouracil | 133.0318 | 72.2 | 0.006806 | − 0.33 | 0.015022 | 1.624164 | pos |
4 | Acetylphosphate | 139.982 | 31.9 | 0.435395 | − 0.23 | 0.03028 | 1.552004 | pos |
5 | 3,4-Dihydroxyphenylglycol | 169.9773 | 92.7 | 0.452329 | − 1.73 | 0.003585 | 1.728516 | pos |
6 | 3,4-Dihydroxymandelic acid | 184.1695 | 126.5 | 1.390554 | 0.72 | 0.028783 | 1.555177 | pos |
7 | N6-Acetyl-L-lysine | 189.1234 | 45.6 | 0.000388 | 0.54 | 0.011194 | 1.671375 | pos |
8 | Thiabendazole | 202.044 | 201.4 | 1.113206 | − 0.4 | 0.009698 | 1.678637 | pos |
9 | Deoxyuridine | 228.1958 | 641.8 | 0.06115 | − 1.35 | 0.00684 | 1.698428 | pos |
10 | Myristic acid | 229.1797 | 412.6 | 1.785623 | − 0.51 | 0.00848 | 1.693119 | pos |
11 | Oleic acid | 282.2787 | 521 | 0.632864 | − 0.74 | 0.035148 | 1.541356 | pos |
12 | 9-cis-Retinal | 285.2195 | 529.9 | 6.226783 | 1.01 | 0.044273 | 1.498674 | pos |
13 | Sphinganine | 302.3042 | 491.1 | 0.969481 | − 0.66 | 0.008316 | 1.789165 | pos |
14 | 1-Arachidonoylglycerol | 361.2723 | 462.4 | 1.648725 | 0.71 | 0.024507 | 1.602941 | pos |
15 | Glycyrrhetinate | 453.3405 | 555.5 | 18.38353 | 8.72 | 2.12E-05 | 1.818695 | pos |
16 | Avermectin A2a aglycone | 616.3658 | 432.8 | 7.6254 | 0.78 | 0.026296 | 1.576102 | pos |
17 | L-Aspartate-semialdehyde | 116.0352 | 48 | 1.06864 | 0.67 | 0.012096 | 1.65956 | neg |
18 | 4-Coumaryl alcohol | 131.0501 | 192.5 | 2.975961 | 2.65 | 0.046341 | 1.527998 | neg |
19 | D-Xylose | 149.0093 | 544.6 | 7.012952 | 0.41 | 0.04028 | 1.476882 | neg |
20 | D-Ribose | 149.9939 | 550.4 | 5.387926 | − 1.55 | 0.00701 | 1.664844 | neg |
21 | Nicotine | 160.9331 | 689.6 | 8.20923 | 2.28 | 1.15E-05 | 1.810164 | neg |
22 | Quinate | 173.0447 | 136.4 | 1.791445 | 0.41 | 0.04958 | 1.503161 | neg |
23 | L-Arginine | 173.1042 | 59.8 | 1.294018 | 0.36 | 0.016083 | 1.593975 | neg |
24 | Guanidinosuccinic acid | 174.9571 | 118.8 | 12.42855 | 3.73 | 0.036359 | 1.51136 | neg |
25 | N-Acetylserotonin | 199.1702 | 518.6 | 5.170116 | 0.22 | 0.048617 | 1.507976 | neg |
26 | Deoxycytidine | 226.0828 | 72.8 | 2.211579 | 0.52 | 0.036608 | 1.477014 | neg |
27 | 9(S)-HPODE | 293.2118 | 462.9 | 0.306945 | 0.95 | 0.010478 | 1.669072 | neg |
28 | 5′-Methylthioadenosine | 297.2452 | 554.8 | 6.130677 | 1.58 | 0.016614 | 1.653746 | neg |
29 | 5-KETE | 317.2107 | 465.3 | 4.728718 | 1.35 | 0.020487 | 1.589074 | neg |
30 | 16(R)-HETE | 319.2256 | 497.6 | 6.96686 | 1.39 | 0.023236 | 1.553453 | neg |
31 | Prostaglandin F2a | 335.2198 | 418 | 7.189313 | 1.18 | 0.043442 | 1.477773 | neg |
32 | Hepoxilin B3 | 335.2206 | 450.3 | 6.562842 | 1 | 0.005992 | 1.673223 | neg |