Fig. 4

THSWD medicated serum influences the proliferation and apoptosis of human UF tissue-derived cells via the PI3K/AKT pathway. A The effects of different drug serum concentrations on cytotoxicity by CCK-8 assay. ***p < 0.001, vs. 0% THSWD-serum; B Proliferative activity of tumor cells by CCK-8 assay; C–D Apoptosis rate of cells derived from human UF tissue by flow cytometry; E–G Expression levels of cleaved caspase-3 and p-AKT/AKT by western blot (n = 3, *p < 0.05, **p < 0.01, ***p < 0.001, vs. negative control; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001, vs. THSWD-serum)