Fig. 5

THSWD-serum effects on proliferation and apoptosis of human UF tissue-derived cells via the miR-21-5p/PTEN axis. A Expression of miR-21-5p in human UF tissue-derived cells by q-PCR; B The interaction between miR-21-5p and PTEN was confirmed by luciferase reporter assay; C Proliferative activity of cells derived from human UF tissues by CCK-8 assay; D–E Apoptosis rate of cells derived from human UF tissues by flow cytometry; F–G Expression levels of cleaved caspase-3 by western blot. (n = 3, *p < 0.05, ***p < 0.001, vs. negative control; ^△△△p < 0.001, vs. NC mimics + h-PTEN-3’UTR-wt; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001, vs. THSWD-serum)