Fig. 3

‘FSM—compounds—arrhythmia—targets’ network construction. A Venn diagram for intersections of target genes from the FSM therapeutic targets dataset and arrhythmia associated targets set. B Heatmap depicting the correlation of combined score among the 33 candidate targets. C Bubble plot for GO and KEGG enrichment analysis of 33 candidate targets in the network. The bubble plot showed the top 5 enriched GO terms and 3 KEGG pathways involved in arrhythmia. D‘FSM—compounds—arrhythmia- targets’ network. Different shapes represent different modules. Rectangle: FSM, diamond: compounds, ellipse: candidate targets, triangle: GO terms, arrow: KEGG pathways. E The cnetplot for top 5 GO CC terms of candidate genes. F The cnetplot for top 5 GO MF terms of candidate genes. G The cnetplot for top 5 GO BP terms of candidate genes. H The cnetplot for top 3 KEGG pathways of candidate genes. I Crosstalk for prominent targets and their related compounds from enriched KEGG pathways from ‘FSM—compounds—arrhythmia—targets’ network. Diagrams were constructed using ggplot2 package (version 3.3.3) R software