Fig. 9

Network biological analysis. A Venn diagram of genes co-regulated by Acu-exo and Sepsis (Acu-exo group: mapping differential target genes in miRNA sequencing to human genes, Sepsis group: genes associated with sepsis in the Human Disease Database). B Network topology map of interacting genes. C Network topology of signaling pathways. D Network topology of genes-source. B-D Diamonds represent interacting genes, signaling pathways and sources, and circles represent co-regulated genes. The color from yellow to red and sizes from small to large represents the degree value from small to large, a higher Degree indicates a closer connection between them