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Fig. 11 | Chinese Medicine

Fig. 11

From: Mechanisms of Xiaozheng decoction for anti-bladder cancer effects via affecting the GSK3β/β-catenin signaling pathways: a network pharmacology-directed experimental investigation

Fig. 11

Kumatakenin regulated the GSK3β/β-catenin signaling pathway in J82 cells. The expression of MMP9, MMP2, vimentin, and GSK3β/β-catenin in J82 cells under kumatakenin treatment (AC). The expression of caspase-3 and Bcl-2/BAX in J82 cells under kumatakenin treatment (D, E). Representative blots are presented with the densitometry results; GAPDH served as a control. Values are presented as the mean ± standard deviation of five independent experiments. *P < 0.05 **P < 0.01 and ***P < 0.001, versus control group

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