Fig. 1From: Ajugol's upregulation of TFEB-mediated autophagy alleviates endoplasmic reticulum stress in chondrocytes and retards osteoarthritis progression in a mouse modelAjugol toxicity, and effects on chondrocyte activity. A Chemical structure of Ajugol. B CCK8 assay results illustrating the viability of chondrocytes treated with various concentrations of Ajugol for 24 h. C Chondrocyte viability after treatment with Ajugol for 12, 24, 48 and 72 h, as detected by CCK8 assay. D Cell viability of TBHP stimulated (30 μM) chondrocytes after treatment with varying concentrations of Ajugol. E EdU staining of TBHP stimulated (30 μM) chondrocytes after treatment with varying concentrations of Ajugol. F Live-dead staining of TBHP stimulated (30 μM) chondrocytes after treatment with varying concentrations of Ajugol. All values are presented as mean ± standard deviation (n = 3). *P < 0.05,**P < 0.01,***P < 0.001Back to article page