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Fig. 2 | Chinese Medicine

Fig. 2

From: Ajugol's upregulation of TFEB-mediated autophagy alleviates endoplasmic reticulum stress in chondrocytes and retards osteoarthritis progression in a mouse model

Fig. 2

Ajugol alleviates TBHP-induced apoptosis and ECM degradation in chondrocytes. A TUNEL staining images showing the effect of different gradients of Ajugol following the addition of 30 μM TBHP. B–E Protein expression levels of CHOP, Bcl-2, and Bax in hondrocytes stimulated with 30 μM TBHP and treated with different concentration gradients of Ajugol. F Immunofluorescence results of CHOP and Bcl-2 in chondrocytes stimulated with 30 μM TBHP and treated with different concentration gradients of Ajugol. G–I Protein levels of Collagen II and MMP13 in each group; J Immunofluorescence staining of Collagen II. All values are presented as mean ± standard deviation (n = 3). *P < 0.05,** P < 0.01,***P < 0.001

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Chinese Medicine

ISSN: 1749-8546

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