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Fig. 5 | Chinese Medicine

Fig. 5

From: Ajugol's upregulation of TFEB-mediated autophagy alleviates endoplasmic reticulum stress in chondrocytes and retards osteoarthritis progression in a mouse model

Fig. 5

Silencing of TFEB reverses the ability of Ajugol to alleviate TBHP-induced endoplasmic reticulum stress. ATFEB mRNA expression after addition of si-TFEB. B–G The expression of PERK-eIF-ATF4 axis related proteins, and the expression of TFEB in the nucleus and cytoplasm. H Immunofluorescence of GRP78, ATF4 in chondrocytes. All values are presented as mean ± standard deviation (n = 3). *P < 0.05,** P < 0.01,***P < 0.001

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Chinese Medicine

ISSN: 1749-8546

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