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Fig. 6 | Chinese Medicine

Fig. 6

From: Ajugol's upregulation of TFEB-mediated autophagy alleviates endoplasmic reticulum stress in chondrocytes and retards osteoarthritis progression in a mouse model

Fig. 6

Silencing of TFEB reverses the anti-apoptotic and anti-ECM degradation effects of Ajugol on chondrocytes. A, C–E Protein expression of CHOP, Bcl-2 and Bax in chondrocytes. B, F, G Protein expression of Collagen II and MMP13 in chondrocytes. H Immunofluorescence of CHOP and Bcl-2 in chondrocytes. I Immunofluorescence of MMP13 and Collagen II in chondrocytes. All values are presented as mean ± standard deviation (n = 3). *P < 0.05,** P < 0.01,***P < 0.001

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