Fig. 1

Therapeutic effect of HGWD on OIPN. A HGWD treatment of OIPN animal model. B Body weight test of mice. C Paw withdrawal threshold induced by mechanical stimulation (Von Frey filament). D Escape behavior score by cold stimulation (4 ℃). Data are expressed as mean ± SEM. HGWD-L: 10 g/kg, HGWD-H: 20 g/kg. #P < 0.05, ##P < 0.01 (compared with Vehicle group); *P < 0.05, **P < 0.01 (compared with OIPN group)