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Fig. 3 | Chinese Medicine

Fig. 3

From: Lycium barbarum polysaccharide inhibits ischemia-induced autophagy by promoting the biogenesis of neural stem cells-derived extracellular vesicles to enhance the delivery of miR-133a-3p

Fig. 3

Autophagy regulation induced by LBP pretreated EVs reduces post-stroke brain injury . A Western blot analysis of Beclin-1, P62, and LC3II proteins in ischemic brain tissue under PBS-treated, NSC-EV treated, and L-NSC-EV treated and H-NSC-EV treated rats. B–C The expression levels of selected proteins detected by Western blot were normalized to the GADPH level of the same sample. E Representative immunofluorescence images between each group as indicated by NeuN staining within the ischemic lesion site. F The quantitative analysis of the cortical neuronal density in ischemia-induced mice at 4 weeks after MCAO. Data are shown as mean ± SD. n = 6 animals per group. Data are statistically different from each other with *P < 0.05, **P < 0.01, and ***P < 0.001

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Chinese Medicine

ISSN: 1749-8546

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