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Fig. 1 | Chinese Medicine

Fig. 1

From: Xinyang tablet ameliorates sepsis-induced myocardial dysfunction by regulating Beclin-1 to mediate macrophage autophagy and M2 polarization through LncSICRNT1 targeting E3 ubiquitin ligase TRAF6

Fig. 1

Bioinformatics analysis of abnormal expression levels of LncSICRNT1 and TRAF6 in sepsis. A Volcano plot of differentially-expressed genes in lncRNA microarray GSE145227 in sepsis; abscissa indicated -log10 (p.value), ordinate indicated logFC, red dots indicated significantly-upregulated genes, and green dots indicated significantly-downregulated genes; B Prediction of RNA-binding domain on the amino acid sequence of TRAF6; C Intersection of the predicted lncRNAs of TRAF6 and downregulated lncRNAs in microarray GSE145227, with the middle part indicating the intersection; D Differential expression of candidate lncRNAs in microarray GSE145227, with green boxplot indicating normal samples and red boxplot indicating sepsis samples. *p < 0.05, ***p < 0.005

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