Table 4 Cellular evaluation of herbal injections and possible mechanisms
From: Pseudo-allergic reactions induced by Chinese medicine injections: a review
Cell | TCMI | Mechanism | References |
|---|---|---|---|
RBL-2H3 | Qingkailing injection | Based on PI3K-Rac1 signaling pathways | Li Q, [77] |
Sodium hesperidin for injection (SAI) | \ | Wang D. [82] | |
Thromboxane for Injection (lyophilized) and Phlegm Fever Clear Injection | Direct action and bypass pathway via activation of the complement system | Song Y. [83] | |
Yiqi Fumai for Injection (Lyophilized) | \ | Fan S, [84] | |
Shuanghuanglian injection | \ | Wang F, [85] | |
Shegan antiviral injection | Associated with increased intracellular Ca2 + concentration | Zhang RR, [78] | |
Shenmai injection | May be related to the solvent Tween-80 | Xiong K, [86] | |
Mao Dongqing injection | \ | Fan NQ, [87] | |
P815 cell | Xiangdan injection | May be related to the mobilization of Ca2+ inward flow | Pang F, [23] |
HUVECs cell | Shuxuening injection | hyperactivation of the mTOR signaling pathway | Wang L, [8] |
RBL-2H3 and P815 cell | Vitamin K1 injection | \ | Xu M, [88] |