Fig. 6

Metabolomics demonstrates the altered TCA cycle pathway in the liver of ACLF rats and the regulatory role of JDNWF. A Schematic diagram of the characteristic metabolic pathways in ACLF group and B JDNWF group. Red-labeled metabolites indicate that this metabolite was elevated in ACLF group or JDNWF group, while blue-labeled metabolites were decreased. C Relative levels of different metabolites in the abnormal metabolic pathways in the liver of ACLF rats. (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)