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Fig. 1 | Chinese Medicine

Fig. 1

From: Combination of Atractylenolide I, Atractylenolide III, and Paeoniflorin promotes angiogenesis and improves neurological recovery in a mouse model of ischemic Stroke

Fig. 1

Combination of compounds promotes cell proliferation in vitro. A CCK8 assay was performed to evaluate the different doses of Atr I, Atr III, and Pae on cell survival. The result demonstrates the toxicity at high concentrations of the compounds. B CCK8 assay was performed to evaluate the effects of Atr I, Atr III, and Pae alone within the non-toxic range, illustrates the efficacy of each compound when used individually. C CCK8 assay was performed to assess the synergistic effects of combining Atr I, Atr III, and Pae on cell proliferation. D Images represent immunofluorescence staining of BrdU. E Bar graph shows the percentage of BrdU positive cells. Data are expressed as mean ± SD. n = 4 per group. *p < 0.05, ***p < 0.001 vs. Control group

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