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Fig. 4 | Chinese Medicine

Fig. 4

From: Danggui Sini decoction alleviates oxaliplatin-induced peripheral neuropathy by regulating gut microbiota and potentially relieving neuroinflammation related metabolic disorder

Fig. 4

DSD attenuated OXA-induced intestinal permeability. A Representative images of colon sections stained with H&E (20 ×). Epithelial cells (blue arrows) and the mucosal layer (black arrow) are indicated. B Representative IHC images showing the expression of tight junction-related proteins in colon tissues (20 ×). Histograms show IOD/ARE (Mean density). C Transmission electron microscopy (2K × , 10K ×) analysis of epithelial junction complex and bridge and mitochondria in colon tissue. *P < 0.05, **P < 0.01, vs. OXA group; n = 3 in every group

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