Table 4 Contents (μg/g, mean ± SD, n = 3) of markers in Gegen Tang granule from four manufacturers
Manufacturers and Batch No. | Puerarin | Paeoniflorin | Cinnamic acid | Daidzain | Glycyrrhizin | Ephedrine | Pseudoephedrine | |
|---|---|---|---|---|---|---|---|---|
A* | Batch No.1 | 374.3 ± 3.1 | 270.5 ± 0.6 | 70.4 ± 0.4 | 52.1 ± 0.4 | 411.4 ± 2.8 | 731.4 ± 2.3 | 242.8 ± 2.3 |
Batch No.2 | 440.8 ± 1.5 | 342.1 ± 2.7 | 89.7 ± 0.5 | 59.8 ± 0.5 | 542.6 ± 2.6 | 938.5 ± 8.8 | 322.4 ± 3.1 | |
Batch No.3 | 738.7 ± 4.1 | 353.8 ± 3.1 | 100.2 ± 0.7 | 131.4 ± 0.9 | 1558.3 ± 12.6 | 1162.0 ± 8.1 | 318.6 ± 2.0 | |
Mean (± SD) | 517.9 ± 194.1 | 322.1 ± 45.1 | 86.8 ± 15.1 | 81.1 ± 43.7 | 837.4 ± 627.7 | 944.0 ± 215.4 | 294.6 ± 44.9 | |
B* | Batch No.1 | 733.4 ± 5.8 | 423.1 ± 2.0 | 72.1 ± 3.8 | 63.2 ± 1.0 | 1584.3 ± 12.2 | 2121.0 ± 7.4 | 482.6 ± 4.2 |
Batch No.2 | 2273.4 ± 21.4 | 1339.6 ± 4.2 | 183.4 ± 1.7 | 302.6 ± 0.7 | 3314.6 ± 14.6 | 2863.4 ± 21.8 | 891.4 ± 3.7 | |
Batch No.3 | 1708.6 ± 11.6 | 1030.7 ± 6.5 | 149.7 ± 0.9 | 228.7 ± 0.8 | 3276.5 ± 23.9 | 1822.6 ± 0.7 | 609.7 ± 3.1 | |
Mean (± SD) | 1571.8 ± 779.1 | 931.1 ± 466.3 | 135.1 ± 57.1 | 198.2 ± 122.6 | 2725.1 ± 988.2 | 2269.0 ± 536.0 | 661.2 ± 209.2 | |
C* | Batch No.1 | 1202.8 ± 14.0 | 4587.7 ± 16.1 | 224.1 ± 0.57 | 138.3 ± 0.8 | 5917.4 ± 39.1 | 2886.8 ± 0.7 | 743.7 ± 0.8 |
Batch No.2 | 1479.4 ± 11.5 | 1672.4 ± 10.4 | 149.6 ± 0.7 | 162.6 ± 0.1 | 1814.2 ± 5.4 | 2293.7 ± 0.2 | 639.6 ± 4.5 | |
Mean (± SD) | 1341.1 ± 19.6 | 3130.1 ± 2061.4 | 186.9 ± 52.7 | 151.5 ± 18.6 | 3865.8 ± 2901.4 | 2590.3 ± 419.4 | 691.7 ± 10.7 | |
D** | Batch No.1 | 5913.6 ± 48.5 | 4899.4 ± 25.5 | 323.6 ± 1.9 | 324.1 ± 0.6 | 5087.1 ± 45.3 | 3740.4 ± 1.0 | 902.4 ± 8.1 |
Batch No.2 | 3417.7 ± 18.5 | 4341.6 ± 24.7 | 238.9 ± 0.6 | 179.6 ± 0.3 | 4958.3 ± 15.4 | 3172.6 ± 0.4 | 1002.4 ± 6.1 | |
Batch No.3 | 3711.5 ± 18.6 | 4124.8 ± 32.5 | 271.4 ± 2.6 | 242.4 ± 0.9 | 4079.6 ± 11.8 | 4577.8 ± 0.8 | 1203.8 ± 6.3 | |
Batch No.4 | 3889.3 ± 19.4 | 3128.7 ± 21.0 | 287.6 ± 2.0 | 263.7 ± 0.8 | 4189.3 ± 20.5 | 4329.6 ± 0.4 | 969.7 ± 5.2 | |
Batch No.5 | 4193.2 ± 17.2 | 3623.3 ± 26.1 | 304.4 ± 2.7 | 269.9 ± 0.7 | 3958.7 ± 17.0 | 3820.3 ± 0.4 | 1134.3 ± 8.5 | |
Batch No.6 | 4362.7 ± 18.6 | 3411.7 ± 14.0 | 313.2 ± 2.3 | 324.1 ± 0.5 | 4672.7 ± 20.1 | 2617.8 ± 0.8 | 933.1 ± 4.9 | |
Batch No.7 | 4438.6 ± 31.1 | 3462.6 ± 7.6 | 327.8 ± 2.3 | 317.8 ± 0.6 | 4729.7 ± 8.5 | 2624.0 ± 0.8 | 959.7 ± 8.0 | |
Mean (± SD) | 4275.2 ± 809.1 | 3856.0 ± 623.4 | 295.3 ± 31.8 | 274.5 ± 53.2 | 4525.0 ± 447.1 | 35554.6 ± 779.1 | 1015.1 ± 111.5 | |