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Table 4 Contents (μg/g, mean ± SD, n = 3) of markers in Gegen Tang granule from four manufacturers

From: Simultaneous determination of multiple marker constituents in concentrated Gegen Tang granule by high performance liquid chromatography

Manufacturers and Batch No. Puerarin Paeoniflorin Cinnamic acid Daidzain Glycyrrhizin Ephedrine Pseudoephedrine
A* Batch No.1 374.3 ± 3.1 270.5 ± 0.6 70.4 ± 0.4 52.1 ± 0.4 411.4 ± 2.8 731.4 ± 2.3 242.8 ± 2.3
Batch No.2 440.8 ± 1.5 342.1 ± 2.7 89.7 ± 0.5 59.8 ± 0.5 542.6 ± 2.6 938.5 ± 8.8 322.4 ± 3.1
Batch No.3 738.7 ± 4.1 353.8 ± 3.1 100.2 ± 0.7 131.4 ± 0.9 1558.3 ± 12.6 1162.0 ± 8.1 318.6 ± 2.0
Mean (± SD) 517.9 ± 194.1 322.1 ± 45.1 86.8 ± 15.1 81.1 ± 43.7 837.4 ± 627.7 944.0 ± 215.4 294.6 ± 44.9
B* Batch No.1 733.4 ± 5.8 423.1 ± 2.0 72.1 ± 3.8 63.2 ± 1.0 1584.3 ± 12.2 2121.0 ± 7.4 482.6 ± 4.2
Batch No.2 2273.4 ± 21.4 1339.6 ± 4.2 183.4 ± 1.7 302.6 ± 0.7 3314.6 ± 14.6 2863.4 ± 21.8 891.4 ± 3.7
Batch No.3 1708.6 ± 11.6 1030.7 ± 6.5 149.7 ± 0.9 228.7 ± 0.8 3276.5 ± 23.9 1822.6 ± 0.7 609.7 ± 3.1
Mean (± SD) 1571.8 ± 779.1 931.1 ± 466.3 135.1 ± 57.1 198.2 ± 122.6 2725.1 ± 988.2 2269.0 ± 536.0 661.2 ± 209.2
C* Batch No.1 1202.8 ± 14.0 4587.7 ± 16.1 224.1 ± 0.57 138.3 ± 0.8 5917.4 ± 39.1 2886.8 ± 0.7 743.7 ± 0.8
Batch No.2 1479.4 ± 11.5 1672.4 ± 10.4 149.6 ± 0.7 162.6 ± 0.1 1814.2 ± 5.4 2293.7 ± 0.2 639.6 ± 4.5
Mean (± SD) 1341.1 ± 19.6 3130.1 ± 2061.4 186.9 ± 52.7 151.5 ± 18.6 3865.8 ± 2901.4 2590.3 ± 419.4 691.7 ± 10.7
D** Batch No.1 5913.6 ± 48.5 4899.4 ± 25.5 323.6 ± 1.9 324.1 ± 0.6 5087.1 ± 45.3 3740.4 ± 1.0 902.4 ± 8.1
Batch No.2 3417.7 ± 18.5 4341.6 ± 24.7 238.9 ± 0.6 179.6 ± 0.3 4958.3 ± 15.4 3172.6 ± 0.4 1002.4 ± 6.1
Batch No.3 3711.5 ± 18.6 4124.8 ± 32.5 271.4 ± 2.6 242.4 ± 0.9 4079.6 ± 11.8 4577.8 ± 0.8 1203.8 ± 6.3
Batch No.4 3889.3 ± 19.4 3128.7 ± 21.0 287.6 ± 2.0 263.7 ± 0.8 4189.3 ± 20.5 4329.6 ± 0.4 969.7 ± 5.2
Batch No.5 4193.2 ± 17.2 3623.3 ± 26.1 304.4 ± 2.7 269.9 ± 0.7 3958.7 ± 17.0 3820.3 ± 0.4 1134.3 ± 8.5
Batch No.6 4362.7 ± 18.6 3411.7 ± 14.0 313.2 ± 2.3 324.1 ± 0.5 4672.7 ± 20.1 2617.8 ± 0.8 933.1 ± 4.9
Batch No.7 4438.6 ± 31.1 3462.6 ± 7.6 327.8 ± 2.3 317.8 ± 0.6 4729.7 ± 8.5 2624.0 ± 0.8 959.7 ± 8.0
Mean (± SD) 4275.2 ± 809.1 3856.0 ± 623.4 295.3 ± 31.8 274.5 ± 53.2 4525.0 ± 447.1 35554.6 ± 779.1 1015.1 ± 111.5
  1. Values are means ± SD of triplicate tests. Single factor ANOVA was performed on each component. Contents of each compound showed significant differences among the four manufacturers (P < 0.05). * Significant differences were observed in different sample batches (P < 0.05). ** No significant difference was observed in the contents of each component in seven batches of GT from manufacturer D (P > 0.05).