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  1. Autophagy is a highly conserved degradation process for long-lived intracellular proteins and organelles mediated by lysosomes. Deficits in the autophagy-lysosome pathway (ALP) have been linked to a variety of...

    Authors: Jie Xu, Xiao-Qi Zhang and Zaijun Zhang

    Citation: Chinese Medicine 2020 15:123

    Content type: Review

    Published on:

  2. Liver ischemia/reperfusion (I/R) injury is an inevitable pathological phenomenon in various clinical conditions, such as liver transplantation, resection surgery, or shock, which is the major cause of morbidit...

    Authors: Zheng Wang, Ping Zhang, Qingqing Wang, Xueping Sheng, Jianbing Zhang, Xiaoyan Lu and Xiaohui Fan

    Citation: Chinese Medicine 2020 15:122

    Content type: Research

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  3. Diabetes is a complex metabolic disease characterized by hyperglycemia, plaguing the whole world. However, the action mode of multi-component and multi-target for traditional Chinese medicine (TCM) could be a ...

    Authors: Yunfei Song, Jianbo Yang, Wenguang Jing, Qi Wang, Yue Liu, Xianlong Cheng, Fei Ye, Jinying Tian, Feng Wei and Shuangcheng Ma

    Citation: Chinese Medicine 2020 15:121

    Content type: Research

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  4. This study was aimed to investigate the therapeutic effects and potential mechanism of higenamine combined with [6]-gingerol (HG/[6]-GR) against doxorubicin (DOX)—induced chronic heart failure (CHF) in rats.

    Authors: Jianxia Wen, Xiao Ma, Ming Niu, Junjie Hao, Ying Huang, Ruilin Wang, Ruisheng Li, Jian Wang and Yanling Zhao

    Citation: Chinese Medicine 2020 15:120

    Content type: Research

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  5. Naoshuantong capsule (NSTC) is an oral Chinese medicine formula composed of Typhae Pollen, Radix Paeoniae Rubra, Curcumae Radix, Gastrodiae Rhizoma and Radix Rhapontici. It has been widely used at the acute an...

    Authors: Lvkeng Luo, Shuling Wu, Ruiqi Chen, Hongyu Rao, Wei Peng and Weiwei Su

    Citation: Chinese Medicine 2020 15:119

    Content type: Research

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  6. Cancer cells through autophagy-mediated recycling to meet the metabolic demands of growth and proliferation. The steroidal saponin 20(S)-ginsenoside Rh2 effectively inhibits the growth and survival of a variet...

    Authors: Jiawen Wang, Shuai Bian, Siming Wang, Song Yang, Wanying Zhang, Daqing Zhao, Meichen Liu and Xueyuan Bai

    Citation: Chinese Medicine 2020 15:118

    Content type: Research

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  7. The use of anti-inflammatory and analgesic drugs such as nonsteroidal anti-inflammatory drugs(NSAIDs) for treating acute gout has limitations, such as adverse reactions in the gastrointestinal tract and toxici...

    Authors: Shuang Ren, Fanyan Meng, Yantong Liu, Yun Meng, Ning Tao, Ruoshi Liu and Jie Zhang

    Citation: Chinese Medicine 2020 15:117

    Content type: Research

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  8. Stroke in Chinese Medicine (CM) includes the concepts of ischemic and hemorrhagic strokes from Western Medicine and is a common disease in Hong Kong. This clinical practice guideline (CPG) aims to evaluate and...

    Authors: Linda L. D. Zhong, Wai Kun, Nannan Shi, Tat Chi Ziea, Bacon F. L. Ng, Ying Gao, Zhaoxiang Bian and Aiping Lu

    Citation: Chinese Medicine 2020 15:116

    Content type: Commentary

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  9. The outbreak of COVID-19 has recently evolved into a global pandemic. Up to July 2020, almost every country has confirmed COVID-19 cases reported worldwide. Many leading experts have predicted that the epidemi...

    Authors: Hua Luo, Mingming Zhao, Dechao Tan, Chang Liu, Lin Yang, Ling Qiu, Yan Gao and Hua Yu

    Citation: Chinese Medicine 2020 15:115

    Content type: Review

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  10. Spleen-deficiency syndrome, an important pathological change in traditional Chinese medicine, has been proven to attribute to intestinal dysbacteriosis. Shengmai Yin (SMY), a classic formula for replenishing q...

    Authors: Yu You, Lin Luo, Yanyan You, Yanjun Lin, Huiling Hu, Yunhui Chen, Chaomei Fu and Tian Xie

    Citation: Chinese Medicine 2020 15:114

    Content type: Research

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  11. Yuzhi Zhixue Granule (YZG) is a traditional Chinese patent medicine for treating excessive menstrual flow caused by ovulatory dysfunctional uterine bleeding (ODUB) accompanied by heat syndrome. However, the un...

    Authors: Jialin Li, Hua Luo, Xinkui Liu, Jingyuan Zhang, Wei Zhou, Siyu Guo, Xiuping Chen, Yingying Liu, Shanshan Jia, Haojia Wang, Bingbing Li, Guoliang Cheng and Jiarui Wu

    Citation: Chinese Medicine 2020 15:113

    Content type: Research

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  12. BaelanChagsangBang (BCB), a herbal formulation consisting of eleven herbs, may be prescribed as a reproductive functional supplement to improve ovulation and implantation during the treatment of infertility an...

    Authors: Songhee Jeon, Quan Feng Liu, Hua Cai, Ha Jin Jeong, Su-Hyun Kim, Dong-Il Kim and Ju-Hee Lee

    Citation: Chinese Medicine 2020 15:112

    Content type: Research

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  13. Ganoderma spore is a minuscule germ cell ejected from Ganoderma gills during its growth maturity period, it has been considered with high exploitable potential in health-care products manufacture.

    Authors: Mei-Ting Liu, Ling-Xiao Chen, Jing Zhao and Shao-Ping Li

    Citation: Chinese Medicine 2020 15:111

    Content type: Research

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  14. Trilobatin, a natural compound, has been found to exhibit anti-diabetic properties in high-fat diet (HFD) and streptozotocin (STZ) induced type 2 diabetic mice. But up to now no research has been reported on t...

    Authors: Min Liu, Lujing Wang, Xigan Li, Yucui Wu, Fei Yin and Jianhui Liu

    Citation: Chinese Medicine 2020 15:110

    Content type: Research

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  15. Allergic rhinitis (AR) is a common symptomatic, inflammatory, and immunological disorder of nasal mucosa. Multiple clinical trials and systematic reviews have implicated acupuncture methods as potentially effe...

    Authors: Zihan Yin, Guoyan Geng, Guixing Xu, Ling Zhao and Fanrong Liang

    Citation: Chinese Medicine 2020 15:109

    Content type: Review

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  16. Around 15% of the Hong Kong population was found to suffer from overactive bladder (OAB), but the current available treatments, such as medication, behavioral therapy and physical therapy are unsatisfactory. P...

    Authors: Zhi-xiu Lin, Ngai Ho Tony Chan, Yiu-keung Kwan, Yu Tat Chan, Hongwei Zhang, Kam-yuk Sylvia Tam, Mei Kwan Lai, Chun-Kam Lee, Kit Ngan, Stella Yin Yuen Tsoi, Yiu Wa Lau, Yan-Fang Xian, Jessica Ching and Yuanqi Guo

    Citation: Chinese Medicine 2020 15:108

    Content type: Research

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  17. Ophiocordyceps sinensis, which is only naturally found in the high-elevation extreme environment of the Tibetan Plateau, has been used in traditional Chinese medicine. Information concerning the evolutionary and ...

    Authors: Jie Liu, Linong Guo, Zongwei Li, Zhe Zhou, Zhen Li, Qian Li, Xiaochen Bo, Shengqi Wang, Junli Wang, Shuangcheng Ma, Jian Zheng and Ying Yang

    Citation: Chinese Medicine 2020 15:107

    Content type: Research

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  18. Neuropathic pain is a debilitating pathological pain condition with a great therapeutic challenge in clinical practice. Currently used analgesics produce deleterious side effects. Therefore, it is necessary to...

    Authors: Chunhao Zhu, Ning Liu, Miaomiao Tian, Lin Ma, Jiamei Yang, Xiaobing Lan, Hanxiang Ma, Jianguo Niu and Jianqiang Yu

    Citation: Chinese Medicine 2020 15:106

    Content type: Review

    Published on:

  19. Migraine is painful disease in which neurotransmitters related to pain transmission play an important role. Hejie Zhitong prescription (HJZT) has been used in the clinic as an effective prescription for the tr...

    Authors: Xinna Wang, Hongfei Zhao, Liming Liu, Ping Niu, Chao Zhai, Jinjian Li, Qiaoli Xu and Dexi Zhao

    Citation: Chinese Medicine 2020 15:105

    Content type: Research

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  20. Moxibustion is one of the major interventions of Chinese medicine (CM). The systematic reviews (SRs) are essential references for evaluating the efficacy and safety of moxibustion interventions. This study aim...

    Authors: Ran Tian, Xuan Zhang, Si-Yao Li, Qi-Ying Aixinjueluo, Wai Ching Lam and Zhao-Xiang Bian

    Citation: Chinese Medicine 2020 15:104

    Content type: Research

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  21. The dry body of the Tokay Gecko (Gekko gecko) is the source of a valuable traditional Chinese medicine, it is therefore listed as a Class II protected animal species in China. Due to increasing market demand and ...

    Authors: Yanyan Su, Dandan Ding, Mengjie Yao, Lan Wu, Gangqiang Dong, Dong Zhang, Shilin Chen and Li Xiang

    Citation: Chinese Medicine 2020 15:103

    Content type: Research

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  22. Scutellaria baicalensis Georgi. (SB) is a common heat-clearing medicine in traditional Chinese medicine (TCM). It has been used for thousands of years in China and its neighboring countries. Clinically, it is mos...

    Authors: Jia-Wen Song, Jia-Ying Long, Long Xie, Lin-Lin Zhang, Qing-Xuan Xie, Hui-Juan Chen, Mao Deng and Xiao-Fang Li

    Citation: Chinese Medicine 2020 15:102

    Content type: Review

    Published on:

  23. The root of Angelica gigas Nakai (Apiaceae) has been traditionally used as an important herbal medicine to treat blood-deficiency-related disorders in Eastern Asian countries, and recently, it has been recognized...

    Authors: Se-Eun Lee, Jung-Hoon Kim, Chiyeon Lim and Suin Cho

    Citation: Chinese Medicine 2020 15:101

    Content type: Research

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  24. Ganoderma sp., such as Ganoderma tsugae (GT), play an important role in traditional Chinese medicine. Ganoderma sp. contains several constituents, including Sacacchin, which has recently drawn attention because i...

    Authors: Meng-Huang Wu, Chuang-Yu Lin, Chun-Yin Hou, Ming-Thau Sheu and Hsi Chang

    Citation: Chinese Medicine 2020 15:100

    Content type: Research

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  25. Diabetic retinopathy (DR) is the leading cause of blindness in many countries. The current treatment for non-proliferative DR (NPDR) using Western medicine (WM) alone is insufficient. At present, the combinati...

    Authors: Xuedong An, De Jin, LiYun Duan, Shenghui Zhao, Rongrong Zhou, Fengmei Lian and Xiaolin Tong

    Citation: Chinese Medicine 2020 15:99

    Content type: Research

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  26. Danggui Buxue Tang (DBT), an ancient Chinese herbal decoction containing Astragali Radix and Angelicae Sinensis Radix at a ratio of 5: 1, is prescribed for menopausal women. Flavonoids and its flavonoid glycos...

    Authors: Rui Guo, Shuchen Guo, Xiong Gao, Huaiyou Wang, Weihui Hu, Ran Duan, Tina T. X. Dong and Karl W. K. Tsim

    Citation: Chinese Medicine 2020 15:98

    Content type: Research

    Published on:

  27. The essential oil is one of the main active ingredients of Amomum villosum Lour. However, volatile compounds are easily lost during the drying, storage and even sample preparation procedure. Therefore, using fres...

    Authors: Ling-Xiao Chen, Yun-Feng Lai, Wei-Xiong Zhang, Jing Cai, Hao Hu, Ying Wang, Jing Zhao and Shao-Ping Li

    Citation: Chinese Medicine 2020 15:97

    Content type: Research

    Published on:

  28. Based on therapy with syndrome differentiation and clinical studies on Xiaochaihu decoction (XCHD), we hypothesize that Modified Xiaochaihu Decoction (MXD) has an ability to ameliorate non-alcoholic fatty live...

    Authors: Siting Gao, Tongzhuang Wang, XueKuan Huang, Yaqian Jin, Yu Xu, Yumeng Xi, Jun Zhang, Yan Luo, Hongling Xu, Hongli Guo, Dazhi Ke and Jianwei Wang

    Citation: Chinese Medicine 2020 15:96

    Content type: Research

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  29. Poor access to healthcare in rural communities causes many people to seek herbalists who use medicinal plants for the treatment of various disease conditions. Most knowledge of traditional herbal medicine make...

    Authors: James Kiamba Mailu, Joseph Mwanzia Nguta, James Mucunu Mbaria and Mitchel Otieno Okumu

    Citation: Chinese Medicine 2020 15:95

    Content type: Research

    Published on:

  30. Coronavirus disease 2019 (COVID-19) pandemic is spreading rapidly around the globe. By the establishment of an integrative system combining both traditional Chinese medicine (TCM) and western medicine, China h...

    Authors: Hua Luo, Yan Gao, Jian Zou, Siyuan Zhang, Hanbin Chen, Qiao Liu, Dechao Tan, Yan Han, Yonghua Zhao and Shengpeng Wang

    Citation: Chinese Medicine 2020 15:94

    Content type: Review

    Published on:

  31. The dry root and rhizome of Ligusticum chuanxiong Hort., or Chuanxiong, has been used as a blood-activating and stasis-removing traditional Chinese medicine for 1000 years. Our previous studies have shown the inh...

    Authors: Yi-Yao Yang, Zhao-Yu Wu, Fang-Bo Xia, Hao Zhang, Xu Wang, Jian-Li Gao, Feng-Qing Yang and Jian-Bo Wan

    Citation: Chinese Medicine 2020 15:93

    Content type: Research

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  32. Loki zupa formula is kind of a traditional medicines which used to treat airway diseases, especially those caused by abnormal phlegm, such as cough, asthma and chronic bronchitis. The study aim was to explore ...

    Authors: Nabijan Mohammadtursun, Qiuping Li, Muhammadjan Abuduwaki, Shan Jiang, Hu Zhang, Jing Sun and Jingcheng Dong

    Citation: Chinese Medicine 2020 15:92

    Content type: Research

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  33. Sigesbeckia glabrescens Makino (SG) has been traditionally used for rheumatism and joint protection. However, the anti-arthritic effects and underling mechanisms of SG have not been demonstrated. In this study, w...

    Authors: Qiu Shuo Ma, Ke-Gang Linghu, Tian Zhang, Guan Ding Zhao, Wei Xiong, Shi Hang Xiong, Mingming Zhao, Wei Xu, Juan Yu and Hua Yu

    Citation: Chinese Medicine 2020 15:91

    Content type: Research

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  34. Due to the lack of enough interaction data among compositions, targets and diseases, it is difficult to construct a complete network of Traditional Chinese Medicine (TCM) that comprehensively reflects active c...

    Authors: Mengjie Rui, Hui Pang, Wei Ji, Siqi Wang, Xuefei Yu, Lilong Wang and Chunlai Feng

    Citation: Chinese Medicine 2020 15:90

    Content type: Research

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  35. Liver diseases and related complications are major sources of morbidity and mortality, which places a huge financial burden on patients and lead to nonnegligible social problems. Therefore, the discovery of no...

    Authors: Jianzhi Wu, Guangrui Huang, Yajing Li and Xiaojiaoyang Li

    Citation: Chinese Medicine 2020 15:89

    Content type: Review

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  36. Rhubarb (also named Rhei or Dahuang), one of the most ancient and important herbs in traditional Chinese medicine (TCM), belongs to the Rheum L. genus from the Polygonaceae family, and its application can be trac...

    Authors: Hong Xiang, Jiaxin Zuo, Fangyue Guo and Deshi Dong

    Citation: Chinese Medicine 2020 15:88

    Content type: Review

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  37. Senile osteoporosis (SOP), which is caused by unbalanced bone remodeling, leads to significant economic and societal burdens globally. The combination of Epimedii Folium (EF) and Ligustri Lucidi Fructus (LLF) ser...

    Authors: Xiu-Feng Tang, Zi-Tong Ma, Ying-Ying Gao, Han Wang, Xiao-Xi Li, Ping Yu and Ren-Hui Liu

    Citation: Chinese Medicine 2020 15:87

    Content type: Research

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  38. Daodi medicinal materials (DMMs), with unique characteristics and specific ecological growing environments, are recognized as high-quality medicinal products of Chinese medicinal materials (CMMs). The quality eva...

    Authors: Xindan Liu, Ying Zhang, Menghua Wu, Zhiguo Ma, Zihan Huang, Fang Tian, Sihan Dong, Simin Luo, Yu Zhou, Jinju Zhang, Nanxin Li, Xiaofang He and Hui Cao

    Citation: Chinese Medicine 2020 15:86

    Content type: Review

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  39. Panax notoginseng is a highly valuable medicinal plant. Reduced P. notoginseng yield is a common and serious problem that arises in a continuous cropping system. Variation in the composition and function of soil ...

    Authors: Mengzhi Li, Zhongjian Chen, Jun Qian, Fugang Wei, Guozhuang Zhang, Yong Wang, Guangfei Wei, Zhigang Hu, Linlin Dong and Shilin Chen

    Citation: Chinese Medicine 2020 15:85

    Content type: Research

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  40. Huyang Yangkun Formula (HYYKF) was developed based on theory of traditional Chinese medicine as well as clinical experience and used to improve ovarian function of premature ovarian insufficiency (POI) patient...

    Authors: Meifang Li, Li Xie, Yang Li, Jian Liu, Guangning Nie and Hongyan Yang

    Citation: Chinese Medicine 2020 15:83

    Content type: Research

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  41. Alzheimer’s disease (AD) is one of the most common diseases in elderly people with a high incidence of dementia at approximately 60–80%. The pathogenesis of AD was quite complicated and currently there is no u...

    Authors: Zhiling Fang, Yuqing Tang, Jiaming Ying, Chunlan Tang and Qinwen Wang

    Citation: Chinese Medicine 2020 15:82

    Content type: Review

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  42. Ulcerative colitis (UC) is a chronic nonspecific inflammatory disease of the colon and rectum with unknown etiology, and its symptoms include bloody diarrhea, abdominal pain, and hematochezia. Traditional Chin...

    Authors: Yanyan Wei, Ning Jiang, Tuo Liu, Chang Liu, Wen Xiao, Likeng Liang, Tongming Li and Yang Yu

    Citation: Chinese Medicine 2020 15:81

    Content type: Research

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  43. Glycine tabacina (Labill.) Benth, one of the traditional Chinese herbal medicines, has been used for treatment of nephritis, osteoporosis, rheumatism, and menopausal syndrome. The aim of this study was to illumin...

    Authors: Lihua Tan, Yanbei Tu, Kai Wang, Bing Han, Hongquan Peng and Chengwei He

    Citation: Chinese Medicine 2020 15:79

    Content type: Research

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  44. Coronavirus disease 2019 (COVID-19) is a new global public health emergency. The therapeutic benefits of Cold‒Damp Plague Formula (CDPF) against COVID-19, which was used to treat “cold‒dampness stagnation in t...

    Authors: Lin Han, Xiu-Xiu Wei, Yu-Jiao Zheng, Li-Li Zhang, Xin-Miao Wang, Hao-Yu Yang, Xu Ma, Lin-Hua Zhao and Xiao-Lin Tong

    Citation: Chinese Medicine 2020 15:78

    Content type: Research

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  45. Cisplatin (CDDP) is a chemotherapeutic drug which also causes adverse side effects. Glechoma hederacea is a traditional Chinese herb belonging to the Labiatae family and has many biological activities. Our previo...

    Authors: Su-Tze Chou, Bing-Ying Ho, Yu-Ting Tai, Chun-Jen Huang and Wen-Wan Chao

    Citation: Chinese Medicine 2020 15:77

    Content type: Research

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  46. Traditional Chinese medicine (TCM) are becoming more and more popular all over the world. However, quality issues of TCM may lead to medical incidents in practice and therefore quality control is essential to ...

    Authors: Fong Leong, Xue Hua, Mei Wang, Tongkai Chen, Yuelin Song, Pengfei Tu and Xiao-Jia Chen

    Citation: Chinese Medicine 2020 15:76

    Content type: Review

    Published on: