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  1. Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovitis. Pien Tze Huang (PZH) is a Chinese patent medicine with anti-inflammatory and immunomodulatory effects. However, whether PZH could ...

    Authors: YongQi Deng, Hui Luo, Jun Shu, Haiyang Shu, Cheng Lu, Ning Zhao, Yun Geng, Xiaojuan He and Aiping Lu

    Citation: Chinese Medicine 2020 15:30

    Content type: Research

    Published on:

  2. Alzheimer’s disease (AD) is ranked as the most prevalent neurodegenerative disease. However, the exact molecular mechanisms underlying pathophysiological alterations in AD remain unclear, especially at the pro...

    Authors: Youna Xie, Lingli Yan, Haitao Zeng, Weineng Chen, Jia-Hong Lu, Jian-Bo Wan, Huanxing Su and Xiaoli Yao

    Citation: Chinese Medicine 2020 15:29

    Content type: Research

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  3. Colorectal cancer, one of the most common digestive tumors with high mortality and morbidity worldwide, currently lacks effective therapies available to improve the prognosis. This study was aimed to investiga...

    Authors: Liu-Lin Xiong, Ruo-Lan Du, Lu-Lu Xue, Ya Jiang, Jin Huang, Li Chen, Jia Liu and Ting-Hua Wang

    Citation: Chinese Medicine 2020 15:28

    Content type: Research

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  4. Oligomannuronates (OM) are natural products from alginate that is frequently used as food supplement. The aim of this study was to investigate the in vitro protective effects of OM on RINm5F cells against huma...

    Authors: Xi Liu, Qiong Li, Xiaolei Cheng, Zhichun Liu, Xiaoliang Zhao, Shuai Zhang, Guangli Yu, Xia Zhao and Jiejie Hao

    Citation: Chinese Medicine 2020 15:27

    Content type: Research

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  5. The prediction of drug-target interaction from chemical and biological data can advance our search for potential drug, contributing to a therapeutic strategy for pancreatic adenocarcinoma (PAAD). We aim to ide...

    Authors: Han Liu, Qi Zhou, Wenjuan Wei, Bing Qi, Fen Zeng, Nabuqi Bao, Qian Li, Fangyue Guo and Shilin Xia

    Citation: Chinese Medicine 2020 15:26

    Content type: Research

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  6. Traditional Chinese medicine (TCM) encompasses numerous herbal formulas which play critical therapeutic roles through “multi-components, multi-targets and multi-pathways” mechanisms. Exploring the interaction ...

    Authors: Daiyan Zhang, Yun Zhang, Yan Gao, Xingyun Chai, Rongbiao Pi, Ging Chan and Yuanjia Hu

    Citation: Chinese Medicine 2020 15:25

    Content type: Research

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  7. Jowiseungki decoction (JSD) is a prescription commonly used for the treatment of diabetic complications or diabetic nephropathy (DN) in traditional medicine clinics. However, the underlying therapeutic mechani...

    Authors: Xianglong Meng, Junnan Ma, Seok Yong Kang, Hyo Won Jung and Yong-Ki Park

    Citation: Chinese Medicine 2020 15:24

    Content type: Research

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  8. Tamoxifen (TAM) is a cell type-specific anti-estrogen and is applied to improve the survival of patients with estrogen receptor positive (ER +) breast cancer. However, long-term TAM use can induce serious drug...

    Authors: Hong-Yan Lin, Hong-Wei Han, Yin-Song Wang, De-Liu He, Wen-Xue Sun, Lu Feng, Zhong-Ling Wen, Min-Kai Yang, Gui-Hua Lu, Xiao-Ming Wang, Jin-Liang Qi and Yong-Hua Yang

    Citation: Chinese Medicine 2020 15:23

    Content type: Research

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  9. Chinese herbs have been widely used for thousands of years. In order to kill or control insects and fungus during the cultivation of herb plants, pesticides have played a significant role. More than 30 kinds o...

    Authors: Jinchao Wei, Yan Xue, Jiayi Dong, Shuangpeng Wang, Hao Hu, Hao Gao, Peng Li and Yitao Wang

    Citation: Chinese Medicine 2020 15:22

    Content type: Research

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  10. Qishen granules (QSG) has been applied to treat heart failure (HF) for decades. Our previous transcriptomics study has suggested that Qishen granules (QSG) could regulate the pathways of cardiac energy metabolism...

    Authors: Kuo Gao, Jian Zhang, Pengrong Gao, Qiyan Wang, Ying Liu, Junjie Liu, Yili Zhang, Yan Li, Hong Chang, Ping Ren, Jinmin Liu, Yong Wang and Wei Wang

    Citation: Chinese Medicine 2020 15:21

    Content type: Research

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  11. Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. However, the exact cellular and molecular mechani...

    Authors: Xin-Xing Li, Xiaoting Zheng, Zhenjie Liu, Qiongming Xu, Hongzhen Tang, Jianfang Feng, Shilin Yang, Chi Teng Vong, Hongwei Gao and Yitao Wang

    Citation: Chinese Medicine 2020 15:20

    Content type: Research

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  12. Danmu preparations (Danmu Capsule and Danmu Syrup), which are made from Nauclea officinalis stem extracts, have good clinical efficacy in acute tonsillitis, acute pharyngitis and upper respiratory tract infection...

    Authors: Nanxin Li, Jinju Zhang, Ying Zhang, Zhiguo Ma, Jinhong Liao, Hui Cao and Menghua Wu

    Citation: Chinese Medicine 2020 15:19

    Content type: Research

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  13. Quality evaluation of multi-species resourced herb medicine (MSRHM) is a main problem for quality control of herb medicine. Current quality evaluation methodology lost consideration of species discrepancy. New...

    Authors: Zeyun Li, Yue Du, Yongliang Yuan, Xiaojian Zhang, Zhengtao Wang and Xin Tian

    Citation: Chinese Medicine 2020 15:16

    Content type: Research

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  14. In the original publication of this article [1], the English official name of the affiliation 1 has been changed to “Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China”.

    Authors: Yongliang Huang, Shanshan Wang, Li Liu, Wei Peng, Jiaolong Wang, Ying Song, Qianghua Yuan, Xing Yuan and Chunjie Wu

    Citation: Chinese Medicine 2020 15:14

    Content type: Correction

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    The original article was published in Chinese Medicine 2019 14:17

  15. Cancer-induced bone pain (CIBP) presents a multiple-mechanism of chronic pain involving both inflammatory and neuropathic pain, and its pathogenesis is closely related to endogenous descending system of pain c...

    Authors: Chunpeng Zhang, Chen Xia, Xiaowen Zhang, Weimin Li, Xuerong Miao and Qinghui Zhou

    Citation: Chinese Medicine 2020 15:13

    Content type: Research

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  16. Ophiorrhiza pumila, belonging to the genus Ophiorrhiza (Rubiaceae), is distributed throughout tropical and subtropical Asia. In this study, we evaluated for the first time the anti-proliferation and anti-migratio...

    Authors: Hui Liu, Wanqin Liao, Lixia Fan, Zhaoguang Zheng, Dahai Liu, Qing-Wen Zhang, Anping Yang and Fang Liu

    Citation: Chinese Medicine 2020 15:11

    Content type: Research

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  17. The standards for reporting interventions in clinical trials of cupping (STRICTOC), in the form of a checklist and explanations for users, were designed to improve reporting of cupping trials, particularly the...

    Authors: Xuan Zhang, Ran Tian, Wai Ching Lam, Yuting Duan, Fan Liu, Chen Zhao, Taixiang Wu, Hongcai Shang, Xudong Tang, Aiping Lyu and Zhaoxiang Bian

    Citation: Chinese Medicine 2020 15:10

    Content type: Research

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  18. Our previous clinical evidence suggested that the direct application of “Sanse powder” the main ingredient of “Yiceng” might represent an alternative treatment for knee osteoarthritis. However, the mechanism u...

    Authors: Peng Wu, Zhengquan Huang, Jinjun Shan, Zichen Luo, Nongshan Zhang, Songjiang Yin, Cunsi Shen, Runlin Xing, Wei Mei, Yancheng Xiao, Bo Xu, Jun Mao and Peimin Wang

    Citation: Chinese Medicine 2020 15:9

    Content type: Research

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  19. Atherosclerosis, the underlying cause of the majority of cardiovascular diseases, is a lipid-driven, inflammatory disease of the large arteries. Atherosclerotic cardiovascular disease (ASCVD) threatens human l...

    Authors: Zhihua Peng, Hong Zhan, Yijia Shao, Yan Xiong, Lijin Zeng, Cong Zhang, Zhihao Liu, Zhenhua Huang, Huanxing Su and Zhen Yang

    Citation: Chinese Medicine 2020 15:8

    Content type: Research

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  20. Investigation of aged Chinese herbal materials will help us to understand their use and sources in ancient time and broaden the historical perspective of Chinese material medica. To reach this aim, the basic u...

    Authors: Yusheng Jia, Mengmeng Sun, Yuhua Shi, Zhihui Zhu, Eduard van Wijk, Roeland van Wijk, Tinde van Andel and Mei Wang

    Citation: Chinese Medicine 2020 15:6

    Content type: Research

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  21. Diabetic retinopathy (DR) is a serious microvascular complication of diabetes and remains the leading cause of blindness in adults. Retinal inflammation is playing a crucial role in the development of DR, and ...

    Authors: Bing Pang, Min Li, Jun Song, Qing-wei Li, Jia Wang, Sha Di, Xiao-lin Tong and Qing Ni

    Citation: Chinese Medicine 2020 15:5

    Content type: Research

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  22. Diabetic retinopathy (DR) involves extensive retinal damage and is one of the most common and serious complications of diabetes mellitus. Hyperglycemia is the major pathological trigger for diabetic complicati...

    Authors: Hong Yang, Shiquan Gan, Zhaohui Jiang, Xiaomei Song, Tingting Chen, Yini Xu, Lingyun Fu, Yanyan Zhang, Ling Tao and Xiangchun Shen

    Citation: Chinese Medicine 2020 15:4

    Content type: Research

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  23. Crohn’s disease (CD) is a chronic relapsing form of inflammatory bowel disease, seriously threatening human beings health. However, the pathogenesis of CD is still unclear and there is no specific effective dr...

    Authors: Xueliang Sun, Ke Wen, Zhizhong Xu, Zongqi He, Bensheng Wu, Xiao Yang and Xiaopeng Wang

    Citation: Chinese Medicine 2020 15:2

    Content type: Research

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  24. Mulberry (Morus alba L.) leaf tea benefits the control of diabetes in Asian nations. This study was aim to investigate if the flavonoids, which extracts from mulberry leaves, could regulate the metabolism of glyc...

    Authors: Qinghai Meng, Xu Qi, Ying Chao, Qi Chen, Peng Cheng, Xichao Yu, Meiyu Kuai, Jingzhen Wu, Wenwen Li, Qichun Zhang, Yu Li and Huimin Bian

    Citation: Chinese Medicine 2020 15:1

    Content type: Research

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  25. Radix Salviae (Dan-shen in pinyin), a classic Chinese herb, has been extensively used to treat diabetic retinopathy in clinical practice in China for many years. However, the pharmacological mechanisms of Radix S...

    Authors: Chun-Li Piao, Jin-Li Luo, De Jin, Cheng Tang, Li Wang, Feng-Mei Lian and Xiao-Lin Tong

    Citation: Chinese Medicine 2019 14:58

    Content type: Research

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  26. Human carboxylesterases (hCES) are key serine hydrolases responsible for the hydrolysis of a wide range of endogenous and xenobiotic esters. Although it has been reported that some ginsenosides can modulate th...

    Authors: Zhao-Hui Sun, Jing Chen, Yun-Qing Song, Tong-Yi Dou, Li-Wei Zou, Da-Cheng Hao, Hai-Bin Liu, Guang-Bo Ge and Ling Yang

    Citation: Chinese Medicine 2019 14:56

    Content type: Research

    Published on:

  27. The potential adverse effects of conventional oral pharmacotherapy of osteoarthritis (OA) restrict their long-term use. Topical application of a Chinese herbal paste for relieving OA knee pain can be effective...

    Authors: Wing Sum Siu, Wai Ting Shum, Wen Cheng, Chun Wai Wong, Hoi Ting Shiu, Chun Hay Ko, Ping Chung Leung, Christopher Wai Kei Lam and Chun Kwok Wong

    Citation: Chinese Medicine 2019 14:55

    Content type: Research

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  28. Nutraceuticals containing traditional Chinese medicine (TCM) are promoted for use in the management of diabetes. The evidence to support such use is largely unknown. This study aimed to summarise and evaluate ...

    Authors: Junnan Shi, Hao Hu, Joanna Harnett, Xiaoting Zheng, Zuanji Liang, Yi-Tao Wang and Carolina Oi Lam Ung

    Citation: Chinese Medicine 2019 14:54

    Content type: Review

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  29. Baitouweng is a traditional Chinese medicine with a long history of different applications. Although referred to as a single medicine, Baitouweng is actually comprised of many closely related species. It is th...

    Authors: Tingting Zhang, Yanping Xing, Liang Xu, Guihua Bao, Zhilai Zhan, Yanyun Yang, Jiahao Wang, Shengnan Li, Dachuan Zhang and Tingguo Kang

    Citation: Chinese Medicine 2019 14:53

    Content type: Research

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  30. In traditional Chinese medicine (TCM) clinical practice, TCM syndromes help to understand human homeostasis and guide individualized treatment. However, the TCM syndrome changes with disease progression, of wh...

    Authors: Yiyu Lu, Zhaoyuan Fang, Tao Zeng, Meiyi Li, Qilong Chen, Hui Zhang, Qianmei Zhou, Yiyang Hu, Luonan Chen and Shibing Su

    Citation: Chinese Medicine 2019 14:52

    Content type: Research

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  31. Ginkgo biloba is a medicinal plant which contains abundant endophytes and various secondary metabolites. According to the literary about the information of endophytics from Ginkgo biloba, Chaetomium, Aspergillus,...

    Authors: Zhihui Yuan, Yun Tian, Fulin He and Haiyan Zhou

    Citation: Chinese Medicine 2019 14:51

    Content type: Review

    Published on:

  32. Allergic rhinitis (AR) is a common disease. No evidence is available for the clinical application of acupuncture and moxibustion for the management of AR symptoms in Hong Kong. This study aimed to evaluate the...

    Authors: Ting Yiu Yung, Hongwei Zhang, Lap Che Tang, Lang Zhang, Chak On Law, Wai Man Tam, Chun Wai Chan, Heng Chun Chen, Man Hork Lee, Tat Chi Ziea, Fung Leung Ng and Zhi Xiu Lin

    Citation: Chinese Medicine 2019 14:50

    Content type: Research

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  33. Lycium barbarum (wolfberry) has been widely cultivated in China, particularly in northwest regions. However, the fruit size and taste of L. barbarum from different habitats are quite different. Traditionally, onl...

    Authors: Ying Wang, Hongyu Jin, Xiaoxv Dong, Shuang Yang, Shuangcheng Ma and Jian Ni

    Citation: Chinese Medicine 2019 14:49

    Content type: Research

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  34. Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects, as well as regulate auto...

    Authors: Hua Luo, Chi Teng Vong, Hanbin Chen, Yan Gao, Peng Lyu, Ling Qiu, Mingming Zhao, Qiao Liu, Zehua Cheng, Jian Zou, Peifen Yao, Caifang Gao, Jinchao Wei, Carolina Oi Lam Ung, Shengpeng Wang, Zhangfeng Zhong…

    Citation: Chinese Medicine 2019 14:48

    Content type: Review

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  35. Herbal materials are widely used as medicinal products, dietary supplements, food, and spices. With increased consumption, the safety, quality, and efficacy of herbal materials are becoming more relevant. The ...

    Authors: Mengmeng Sun, Shengpeng Wang, Yong Jing, Li Li, Min He, Yusheng Jia, Eduard van Wijk, Yitao Wang, Zhihong Wang and Mei Wang

    Citation: Chinese Medicine 2019 14:47

    Content type: Research

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  36. The side effects caused by Polygoni Multiflori Radix (PMR) and Polygoni Multiflori Radix Praeparata (PMRP) have often appeared globally. There is no research on the changes of endogenous metabolites among PMR-...

    Authors: Zhaoyan Zhang, Liang Yang, Xiaoyan Huang and Yue Gao

    Citation: Chinese Medicine 2019 14:46

    Content type: Research

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  37. Magnolia officinalis Rehd. et Wils, commonly called Houpo, has been used for thousands of years in China as a traditional herbal medicine. The primary processing of Houpo requires sweating treatment, which is a s...

    Authors: Qinahua Wu, Dan Wei, Linlin Dong, Yuping Liu, Chaoxiang Ren, Qianqian Liu, Cuiping Chen, Jiang Chen and Jin Pei

    Citation: Chinese Medicine 2019 14:45

    Content type: Research

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  38. Gastric mucosal lesion (GML) is the initiating pathological process in many refractory gastric diseases. And moxibustion is an increasingly popular alternative therapy that prevents and treats diseases. Howeve...

    Authors: Yuan Zhang, Miao-sen Huang, Cai-chun Liu, Lin-yu Lian, Jia-cheng Shen, Qi-da He, Ying-jie Wang, Long-bin Zhang, Mi Liu and Zong-bao Yang

    Citation: Chinese Medicine 2019 14:44

    Content type: Research

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  39. Trichosanthis semen, the seeds of Trichosanthes kirilowii Maxim. or Trichosanthes rosthornii Harms, has long been used in Korean medicine to loosen bowels and relieve chronic constipation. Although the fruits and...

    Authors: Su Mi Park, Sang Kyu Jeon, Ok Hyeon Kim, Jung Yun Ahn, Chang-Hyun Kim, Sun-Dong Park and Ju-Hee Lee

    Citation: Chinese Medicine 2019 14:43

    Content type: Research

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  40. The dry root and rhizome of Salvia miltiorrhiza Bunge, or Danshen, is a well-known, traditional Chinese medicine. Tanshinones are active compounds that accumulate in the periderm, resulting in red-colored roots. ...

    Authors: Zhilai Zhan, Wentao Fang, Xiaohui Ma, Tong Chen, Guanghong Cui, Ying Ma, Liping Kang, Tiegui Nan, Huixin Lin, Jinfu Tang, Yan Zhang, Changjiangsheng Lai, Zhenli Ren, Yanan Wang, Yujun Zhao, Ye Shen…

    Citation: Chinese Medicine 2019 14:42

    Content type: Research

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  41. Pheretima is a minister drug in Naoxintong capsule (NXTC), a well-known traditional Chinese medicine (TCM) formula for the treatment of cardiovascular and cerebrovascular diseases. Owing to the loss of morphol...

    Authors: Xiaoxiao Zhu, Hoi-Yan Wu, Pang-Chui Shaw, Wei Peng and Weiwei Su

    Citation: Chinese Medicine 2019 14:41

    Content type: Research

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  42. Polysaccharides in carob fruit, including carob bean gum (also known as carob gum, locust bean gum) and carob fiber, are widely used in industries such as food, pharmaceuticals, paper, textile, oil well drilli...

    Authors: Bao-Jie Zhu, Mohamed Zaky Zayed, Hua-Xu Zhu, Jing Zhao and Shao-Ping Li

    Citation: Chinese Medicine 2019 14:40

    Content type: Review

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  43. To investigate the effects and immunological mechanisms of the traditional Chinese medicine Xinjiaxiangruyin on controlling influenza virus (FM1 strain) infection in mice housed in a hygrothermal environment.

    Authors: Ying-Jie Fu, Yu-Qi Yan, Xiao Zheng, Shan-Shan Shi, Sha Wu and Zhen-You Jiang

    Citation: Chinese Medicine 2019 14:39

    Content type: Research

    Published on: