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  1. Psoriasis is a chronic inflammatory genetic disease, mainly manifesting in the skin. Conventional therapies, such as glucocorticosteroids and corticosteroids, have adverse effects that limit drug use. Hence, i...

    Authors: Chenyang Zhang, Xinran Cao, Lixin Zhao, Zitong Ni, Haojie Du, Jiao Qu, Jianxia Zhu, Haiyan Sun, Yang Sun and Zijun Ouyang
    Citation: Chinese Medicine 2024 19:38
  2. Osteoarthritis (OA) is a prevalent global health concern associated with the loss of articular cartilage and subchondral bone. The lack of disease-modifying drugs for OA necessitates the exploration of novel t...

    Authors: Tao Jiang, Jiahui Zhang, Beite Ruan, Xiaobing Xi, Zhuo Yang, Jianmin Liu, Hongyan Zhao, Xing Xu and Min Jiang
    Citation: Chinese Medicine 2024 19:37
  3. Liver cirrhosis is a chronic liver disease with hepatocyte necrosis and lesion. As one of the TCM formulas Wuling Powder (WLP) is widely used in the treatment of liver cirrhosis. However, it’s key functional c...

    Authors: Qinwen Liu, Xiaowei Li, Yi Li, Qian Luo, Qiling Fan, Aiping Lu, Daogang Guan and Jiahui Li
    Citation: Chinese Medicine 2024 19:36
  4. Alzheimer’s disease (AD) is a neurodegenerative disease with insidious onset and progressive development. It is clinically characterized by cognitive impairment, memory impairment and behavioral change. Chines...

    Authors: Zhihan Chen, Xinrui Wang, Simin Du, Qi Liu, Zhifang Xu, Yi Guo and Xiaowei Lin
    Citation: Chinese Medicine 2024 19:35
  5. Astragaloside IV (As-IV) and Tanshinone IIA (Ta-IIA) are the main ingredients of traditional Chinese medicinal Astragalus membranaceus (Fisch.) Bunge and Salvia miltiorrhiza Bunge, respectively, both of which hav...

    Authors: Pan Zhai, Qianyun Chen, Xunxun Wang, Xiaohu Ouyang, Mengling Yang, Yalan Dong, Junyi Li, Yiming Li, Shanshan Luo, Yue Liu, Xiang Cheng, Rui Zhu and Desheng Hu
    Citation: Chinese Medicine 2024 19:34
  6. Fritillariae Cirrhosae Bulbus is an antitussive and expectorant Chinese medicinal material derived from the dried bulbs of six Fritillaria species. In the 2015 edition of the Chinese Pharmacopoeia, the polymerase...

    Authors: Hoi-Yan Wu, Ka-Lok Wong, Sean Tsz-Sum Law, Wenyang Nong, Kwun-Tin Chan, Jerome Ho-Lam Hui, Ge Lin, Wing-Han Chan and Pang-Chui Shaw
    Citation: Chinese Medicine 2024 19:33
  7. Bufei Yishen formula (BYF), a traditional Chinese medicine alleviates COPD symptoms and suppresses airway epithelial inflammation. In this study, we determined whether BYF protects the airway epithelial barrie...

    Authors: Lidan Jia, Xuefang Liu, Xinguang Liu, Qingzhou Guan, Yange Tian, Jiansheng Li and Peng Zhao
    Citation: Chinese Medicine 2024 19:32
  8. Diabetic kidney disease (DKD) represents a microvascular complication of diabetes mellitus. Shenkang Pills (SKP), a traditional Chinese medicine formula, has been widely used in the treatment of DKD and has ob...

    Authors: Yangtian Yan, Ningning Yuan, Yuchi Chen, Yun Ma, Ali Chen, Fujing Wang, Shihua Yan, Zhuo’en He, Jinyue He, Chi Zhang, Hao Wang, Mingqing Wang, Jianxin Diao and Wei Xiao
    Citation: Chinese Medicine 2024 19:31
  9. Optimized New Shengmai Powder (ONSMP) is a traditional Chinese medicine formula with significant anti-heart failure and myocardial fibrosis effects, but the specific molecular biological mechanisms are not ful...

    Authors: Zeyu Zhang, Zhe xu, Shuai Wang, Zhuangzhuang Jia, Zhou zhou, Ci Wang, Shanshan Lin, Yiting Feng, Xianliang Wang and Jingyuan Mao
    Citation: Chinese Medicine 2024 19:30
  10. Postoperative ileus (POI) is a common obstruction of intestinal content passage caused by almost all abdominal operations that seriously strokes the quality of life of patients. Kuanchang-Shu granule (KCSG), a...

    Authors: Wen-Qian Duan, Ming-Chen Cai, Qi-Qi Ma, Peng Huang, Jia-Hui Zhang, Tian-Fu Wei, Dong Shang, Ai-Jing Leng and Jia-Lin Qu
    Citation: Chinese Medicine 2024 19:29
  11. To investigate the effec of the herb-partitioned moxibustion on T-lymphocyte activity in immunosuppressed rats through differential modulation of the immune checkpoint molecules CD28 and CTLA-4.

    Authors: Luojie Xiong, Yuefeng Tian, Xiaoshan Xu, Huifang Wang, Wei Li and Chuntao Zhai
    Citation: Chinese Medicine 2024 19:28
  12. Diabetic kidney disease (DKD) is a prevalent complication of diabetes and the leading cause of end-stage renal disease. Recent evidence suggests that total flavonoids of Astragalus (TFA) has promising effects ...

    Authors: Pei-Yu Liu, Kin-Fong Hong, Ya-Di Liu, Zhong-Yan Sun, Ting-Ting Zhao, Xu-Ling Li, Chi-Chou Lao, Shu-Feng Tan, Hai-Ying Zhang, Yong-Hua Zhao, Ying Xie and You-Hua Xu
    Citation: Chinese Medicine 2024 19:27
  13. Immune checkpoint inhibitors, which have attracted much attention in recent years, have achieved good efficacy, but their use is limited by the high incidence of acquired drug resistance. Therefore, there is a...

    Authors: Hongzheng Wang, Min Huang, Mengyuan Zhu, Chi Su, Yijian Zhang, Hongyu Chen, Yuexin Jiang, Haidi Wang, Qinglong Guo and Shuai Zhang
    Citation: Chinese Medicine 2024 19:26
  14. Osteoarthritis (OA) is the most prevalent degenerative musculoskeletal disease, severely impacting the function of patients and potentially leading to disability, especially among the elderly population. Natur...

    Authors: Shunzheng Fang, Bin Zhang, Wei Xiang, Liujie Zheng, Xiaodong Wang, Song Li, Tongyi Zhang, Daibo Feng, Yunquan Gong, Jinhui Wu, Jing Yuan, Yaran Wu, Yizhen Zhu, Enli Liu and Zhenhong Ni
    Citation: Chinese Medicine 2024 19:25
  15. Encephalitis caused by dengue virus (DENV) is considered a manifestation of severe dengue. Tanreqing injection (TRQ) is a well-known Chinese patented medicine, which has been used to treat brain-related disord...

    Authors: Hefei Huang, Xuemei He, Lingzhu Shi, Jingtao Yu, Zibin Lu, Huihui Cao, Jinying Ou, Xi Chen, Lijun Yan, Jiabin Yang, Wei Zhao, Junshan Liu and Linzhong Yu
    Citation: Chinese Medicine 2024 19:24
  16. Rheum palmatum L. has important medicinal value because it contains biologically active anthraquinones. However, the key genes and TFs involved in anthraquinone biosynthesis and regulation in R. palmatum remain u...

    Authors: Xia Zhao, Feng Yan, Yi-min Li, Jing Tang, Xiao-chen Hu, Zhao Feng, Jing Gao, Liang Peng and Gang Zhang
    Citation: Chinese Medicine 2024 19:23
  17. Traditional Chinese medicine (TCM) has been widely used for several centuries for metabolic diseases, including non-alcoholic fatty liver disease (NAFLD). At present, NAFLD has become the most prevalent form o...

    Authors: Xin Ding, Xu He, Bulang Tang and Tian Lan
    Citation: Chinese Medicine 2024 19:21
  18. Muscle atrophy is characterized by decreased muscle mass, function, and strength. Synthetic glucocorticoids, including dexamethasone (Dexa), are commonly used to treat autoimmune diseases. However, prolonged e...

    Authors: Ahyoung Yoo, Jung-In Kim, Hyunjung Lee, Farida S. Nirmala, Jeong-Hoon Hahm, Hyo Deok Seo, Chang Hwa Jung, Tae Youl Ha and Jiyun Ahn
    Citation: Chinese Medicine 2024 19:20
  19. Mahuang Fuzi decoction (MGF) is composed of three herb medicines that has been clinically used to treat inflammatory diseases for a long history. At present, more and more active phytochemicals’ aggregations h...

    Authors: Luping Yang, Xiang Zhang, Zhijia Wang, Xiaoyu Lin, Yaozhi Zhang, Jihui Lu, Linying Wu, Shuchang Yao, Wenguang Jing, Xuemei Huang and Penglong Wang
    Citation: Chinese Medicine 2024 19:19
  20. In Traditional Chinese Medicine (TCM) theory, cold dampness obstruction is one of the common syndromes of osteoarthritis. Therefore, in clinical practice, the main treatment methods are to dispel wind, remove ...

    Authors: Longmei Zhao, Shasha Zhou, SiWei Wang, Rui Wu, Qingliang Meng, Zhenbin Li, Jiangyun Peng, Ying Liu, Min Lu, Ming Li, Caifeng Zhu, Yue Sun, Yanlin He, Yue Jin, Jingyue Gao, Shumin Zhang…
    Citation: Chinese Medicine 2024 19:18
  21. Cancer remains one of the leading causes of mortality worldwide. The search for novel and effective anticancer agents has been a significant area of research. Dibenzocyclooctadiene lignans (DBCLS), derived fro...

    Authors: Karolina Jafernik, Sara Motyka, Daniela Calina, Javad Sharifi-Rad and Agnieszka Szopa
    Citation: Chinese Medicine 2024 19:17
  22. Cholesterol gallstone (CG) disease is a worldwide common disease characterized by cholesterol supersaturation in gallbladder bile. Ganoderma lucidum polysaccharide (GLP) has been shown to possess various benefici...

    Authors: Dan Huang, Shuang Shen, Qian Zhuang, Xin Ye, Yueqin Qian, Zhixia Dong and Xinjian Wan
    Citation: Chinese Medicine 2024 19:16
  23. COVID-19 is continuing to ravage globally and has resulted in a huge health and financial burden. Chinese proprietary medicines, such as Lianhua Qingwen (LHQW) and Huoxiang Zhengqi (HXZQ) capsules, have been r...

    Authors: Hui Mo, Man-Fei Zhou, Edmundo Patricio Lopes Lao, Ka-Kei Chan, On-Na Lai, Man-In Ho, Kin-Wa Wong, Ka-Meng Ho, Kin-Tim Sio, Keng-Lam Fong, Yong-Hua Zhao, Seng-Ip Cheang and Iek-Long Lo
    Citation: Chinese Medicine 2024 19:15
  24. Chinese medicine processing (CMP) is a unique pharmaceutical technology that distinguishes it from natural medicines. Current research primarily focuses on changes in chemical components to understand the mech...

    Authors: Bing Yang, Zhubin Zhang, Jinjing Song, Tianhao Qi, Jingqi Zeng, Liang Feng and Xiaobin Jia
    Citation: Chinese Medicine 2024 19:14
  25. Osteoking has been used for fracture therapy with a satisfying clinical efficacy. However, its therapeutic properties and the underlying mechanisms remain elusive.

    Authors: Suya Zhang, Yudong Liu, Zhaochen Ma, Shuangrong Gao, Lin Chen, Honggang Zhong, Chu Zhang, Tao Li, Weiheng Chen, Yanqiong Zhang and Na Lin
    Citation: Chinese Medicine 2024 19:13
  26. The role of pyroptosis in kidney disease is limited and incomplete. Quercetin, a flavonoid compound present in a variety of fruits, vegetables, and plants, has shown antioxidant and anti-inflammatory propertie...

    Authors: Xianli Gao, Caiyun Guo, Wenjun Li, Yingdong Deng, Wenjun Ning, Jiaqi Xie, Xiaoying Zhan, Youling Fan, Hongtao Chen, Zengping Huang and Jun Zhou
    Citation: Chinese Medicine 2024 19:11
  27. Qing-Zao-Jiu-Fei Decoction (QZJFD) is a famous herbal formula commonly prescribed for the treatment of lung-related diseases in the ancient and modern times. Trichosanthis Fructus (TF) and Fritillariae Thunbergii...

    Authors: Jia-Qian Zhu, Yuan-Yang Tian, Kam Leung Chan, Zhen Hu, Qing-Qing Xu, Zhi-Xiu Lin and Yan-Fang Xian
    Citation: Chinese Medicine 2024 19:10
  28. Wu-tou decoction (WTD), a traditional Chinese medicine prescription, is used to treat rheumatoid arthritis (RA). It works by controlling intestinal flora and its metabolites, which in turn modulates the inflam...

    Authors: Di Yang, Xiaoxu Cheng, Meiling Fan, Dong Xie, Zhiqiang Liu, Fei Zheng, Yulin Dai, Zifeng Pi and Hao Yue
    Citation: Chinese Medicine 2024 19:9
  29. The Zhizi Chuanxiong herb pair (ZCHP) can delay pathological progression of atherosclerosis (AS); however, its pharmacological mechanism remains unclear because of its complex components. The purpose of curren...

    Authors: Yan Zhang, Yifei Qi, Zijun Jia, Yiming Li, Liqi Wu, Qingbing Zhou and Fengqin Xu
    Citation: Chinese Medicine 2024 19:8
  30. Sanguinarine chloride (S.C) is a benzophenanthrine alkaloid derived from the root of sanguinaria canadensis and other poppy-fumaria species. Studies have reported that S.C exhibits antioxidant, anti-inflammato...

    Authors: Shanhui Liu, Yan Tao, Shan Wu, Jiawei Lin, Shengjun Fu, Jianzhong Lu, Jing Zhang, Beitang Fu, Erdong Zhang, Jing Xu, Jiaxuan Wang, Lanlan Li, Lei Zhang and Zhiping Wang
    Citation: Chinese Medicine 2024 19:7
  31. Prunella vulgaris polysaccharide extracted by hot water and 30% ethanol precipitation (PVE30) was reported to possess potent antiviral effects against herpes simplex virus (HSV) infection. However, its anti-HSV m...

    Authors: Xuanlei Zhong, Yibo Zhang, Man Yuan, Lin Xu, Xiaomei Luo, Rong Wu, Zhichao Xi, Yang Li and Hongxi Xu
    Citation: Chinese Medicine 2024 19:6
  32. The synthetic liver X receptor ligand (LXR) T0901317 (T0) has been reported to attenuate atherosclerosis (AS) without hyperglyceridemia due to innovative drug combination or nano-sized drug delivery. Given the...

    Authors: Qian Chen, Sijian Wang, Ruixia Bao, Dan Wang, Yuzheng Wu, Yi Zhang, Mengyang Liu and Tao Wang
    Citation: Chinese Medicine 2024 19:5
  33. Usenamine A, a novel natural compound initially isolated from the lichen Usnea longissima, has exhibited promising efficacy against hepatoma in prior investigation. Nevertheless, the underlying mechanisms respons...

    Authors: Ailin Yang, Huiming Huang, Jinxin Xie, Yingying Tian, Longyan Wang, Dongxiao Liu, Xuejiao Wei, Peng Tan, Xingyun Chai, Xiaojun Zha, Pengfei Tu and Zhongdong Hu
    Citation: Chinese Medicine 2024 19:4
  34. Prognosis is critically important in stroke cases, with angiogenesis playing a key role in determining outcomes. This study aimed to investigate the potential protective effects of Atractylenolide I (Atr I), A...

    Authors: Haiyan Li, Wantong Yu, Yong Yang, Sijie Li, Jun Xu, Chen Gao, Wei Zhang, Wenjie Shi, Kunlin Jin, Xunming Ji and Changhong Ren
    Citation: Chinese Medicine 2024 19:3
  35. Determination of batch-to-batch consistency of botanical drugs (BDs) has long been the bottleneck in quality evaluation primarily due to the chemical diversity inherent in BDs. This diversity presents an obsta...

    Authors: Zhu Han, Jiandong Zhao, Yu Tang and Yi Wang
    Citation: Chinese Medicine 2024 19:2
  36. Despite continued advances in prevention and treatment strategies, cardiovascular diseases (CVDs) remain the leading cause of death worldwide, and more effective therapeutic methods are urgently needed. Polygonat...

    Authors: Hongyuan Lin, Wenhui Wang, Mengqi Peng, Yifan Kong, Xiaowei Zhang, Xiaohong Wei and Hongcai Shang
    Citation: Chinese Medicine 2024 19:1
  37. Gossypol, a polyphenolic aldehyde derived from cottonseed plants, has seen a transformation in its pharmaceutical application from a male contraceptive to a candidate for cancer therapy. This shift is supporte...

    Authors: Danijela Paunovic, Jovana Rajkovic, Radmila Novakovic, Jelica Grujic-Milanovic, Reham Hassan Mekky, Dragos Popa, Daniela Calina and Javad Sharifi-Rad
    Citation: Chinese Medicine 2023 18:163
  38. To evaluate the clinical efficacy and safety of commonly used oral Chinese patent medicines for the treatment of coronary heart disease combined with hyperlipidemia in clinical practice through a network meta-...

    Authors: Zhenyu Yang, Jixin Li, Bogeng Zhou, Xuan Ji, Jianying Yuan, Junchen Yan, Xilei Nan and Dandan Guo
    Citation: Chinese Medicine 2023 18:162
  39. Salvianolic acid B (Sal B), a water-soluble phenolic compound derived from Salvia miltiorrhiza Bunge, is commonly used in Traditional Chinese Medicine to treat cardiovascular disease. In our previous study, Sal B...

    Authors: Hong Luo, Lingyun Fu, Xueting Wang, Yini Xu, Ling Tao and Xiangchun Shen
    Citation: Chinese Medicine 2023 18:161
  40. ( −)-Epigallocatechin-3-gallate (EGCG), a bioactive polyphenol isolated from green tea, has recently garnered attention for its potential protective role against acute myocardial infarction (MI) via inhibiting...

    Authors: Chaoshi Qin, Tingting Wang, Ni Qian, Jing Liu, Rong Xi, Qing Zou, Hui Liu and Xiaolin Niu
    Citation: Chinese Medicine 2023 18:160
  41. Chronic hepatitis B (CHB) remains a major world's most serious public health issues. Despite the remarkable effect of nucleos(t)ide analogues (NAs) in inhibiting hepatitis B virus (HBV) deoxyribonucleic acid (...

    Authors: Feilin Ge, Yan Yang, Zhaofang Bai, Lanlan Si, Xuemei Wang, Jia Yu, Xiaohe Xiao, Yan Liu and Zhigang Ren
    Citation: Chinese Medicine 2023 18:159
  42. Rhein can significantly delay the progression of chronic nephropathy. However, its mechanism of action has not been adequately elaborated, which hinders its extensive clinical application. In this work, the ef...

    Authors: Li Wang, Xixi Yu, Hongju Li, Dahong He, Su Zeng and Zheng Xiang
    Citation: Chinese Medicine 2023 18:158
  43. Acute-on-chronic liver failure (ACLF) is a refractory disease with high mortality, which is characterized by a pathophysiological process of inflammation-related dysfunction of energy metabolism. Jieduan-Niwan...

    Authors: Jiajun Liang, Xiaoyi Wei, Weixin Hou, Hanjing Wang, Ruimin Ma, Yanbin Gao, Yuqiong Du and Qiuyun Zhang
    Citation: Chinese Medicine 2023 18:157
  44. Synovial neovascularization promotes rheumatoid arthritis (RA) progression. Baihu guizhi decoction (BHGZD) has a potential in restricting this pathological change of RA.

    Authors: Xia Mao, Xiangying Yan, Congchong Li, Yudong Liu, Yanqiong Zhang and Na Lin
    Citation: Chinese Medicine 2023 18:156
  45. Myocardial ischemia (MI) can cause angina, myocardial infarction, and even death. Angiogenesis is beneficial for ensuring oxygen and blood supply to ischemic tissue, promoting tissue repair, and reducing cell ...

    Authors: Qi Chen, QingYang Xu, Huilin Zhu, Junyi Wang, Ning Sun, Huimin Bian, Yu Li and Chao Lin
    Citation: Chinese Medicine 2023 18:155
  46. Honokiol is a neolignan biphenol found in aerial parts of the Magnolia plant species. The Magnolia plant species traditionally belong to China and have been used for centuries to treat many pathological condition...

    Authors: Md. Faysal, Jishan Khan, Mehrukh Zehravi, Nikhil Nath, Laliteshwar Pratap Singh, Saloni Kakkar, Rajashekar Perusomula, Pathan Amanulla Khan, Firzan Nainu, Mohammed Asiri, Sharuk L. Khan, Rajib Das, Talha Bin Emran and Polrat Wilairatana
    Citation: Chinese Medicine 2023 18:154
  47. The successful launch of icaritin, a therapeutic drug for liver cancer derived from Epimedium brevicornu, has provided new impetus for the development of prenylated flavonoids in the field of oncology. Flemingia ...

    Authors: Baolin Wang, Qinqin Wang, Renyikun Yuan, Shilin Yang, Meilin Lu, Fuhong Yuan, Zhidan Dong, Menghuan Mo, Qiming Pan and Hongwei Gao
    Citation: Chinese Medicine 2023 18:153