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Table 2 Relative uterotrophic and anti-uterotrophic activities

From: Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors

ERr 731 (μg/kg BW/d) Estradiol (mg/kg BW/d)
0 0.5 4
0 100 211.5 ± 42.7*** 576.6 ± 220***/623.8 ± 35.6***
0.1 75.5 ± 9.2/97.3 ± 24.9 189.3 ± 46.1*** -/-
1 85 ± 8.7 162.8 ± 35.1*** -/-
10 103.3 ± 15.2 182.5 ± 31.7*** -/-
100 122.9 ± 13.7/104.2 ± 19.6 130 ± 18.1*/++ -/-
  1. Note:
  2. The mean ± SD of uterine wet weights expressed as percentage of untreated controls are shown. If two values are shown, they represent means ± SD from two independent experiments.
  3. *P < 0.05, ***P < 0.001: statistical significance (Student's t-test) if compared to untreated controls
  4. ++P < 0.01: statistical significance (Student's t-test) if compared to low dose estradiol treatment (0.0005 mg/kg BW/d)