ALC ginseng extract suppressed up-regulation of macrophage NO production by the AQ ginseng extract. Murine macrophages (RAW 264.7 cells) were pre-treated with or without the 200 μg/ml ALC ginseng extracts (50, 200 μg/ml), for two hours after which the AQ ginseng extract (50, 200 μg/ml) was added, and the NO contents of the culture supernatants were determined by Griess reaction assay 24 hours later. Three independent experiments were performed and the data were shown as mean ± SD. Datasets were evaluated by ANOVA. * Values P < 0.001 were statistically significant.