Figure 4

Histograms showing the effects of methyl atropine (2 mg/kg, ip) and naloxone (5 mg/kg followed by 2.5 mg/kg, ip) on the effects of auricular acupuncture (AA) in conscious animals with CA-induced inflammation. Baseline values were obtained before the induction of brief anesthesia and CA injection. Paw volume is expressed as percentage increase from the baseline and thermal or pain threshold is shown as percentage change from the baseline. * P < 0.05, comparison between AA and No AA with the same ip injection (vehicle, naloxone or atropine), n = 12 per group.