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Figure 5 | Chinese Medicine

Figure 5

From: Chotosan (Diaoteng San)-induced improvement of cognitive deficits in senescence-accelerated mouse (SAMP8) involves the amelioration of angiogenic/neurotrophic factors and neuroplasticity systems in the brain

Figure 5

CTS administration-induced amelioration of impaired water maze performance of SAMP8 mice with and without ischemic insult. The water maze test was conducted on days 29-40 after T2VO operation. (A) Learning performance of the animals elucidated in the training test. Each data point indicates the mean escape latency ± SD for 6-10 animals in each group. ###P < 0.001, *P < 0.05, and ***P < 0.001 (two-way ANOVA for repeated measurement). (B) Memory retrieval performance elucidated in the probe test. The test was conducted 24 hours after the last training trials. Each datum represents the mean of time spent in the target quadrant ± SD ##P < 0.01 compared with vehicle-treated SAMR1 group. **P < 0.01 compared with respective vehicle-treated sham- or T2VO-SAMP8 group (two-way ANOVA).

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Chinese Medicine

ISSN: 1749-8546

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