Boswellic acids extract attenuates pulmonary fibrosis induced by bleomycin and oxidative stress from gamma irradiation in rats

Table 3 Reduced glutathione concentration and glutathione perosidase activity in RBCs compacted cells and lung tissue homogenate in rat after different treatment conditions

Parameters Groups	GSH		GSH-Px
Parameters Groups	Blood (mg/dl packed RBCs)	Lung (μg/g tissue)	Blood (μg oxidized GSH/min/ml packed RBCs)	Lung (μg oxidized GSH/min/g tissue)
Control	188.00 ± 8.35	206.1 ± 4.20	272.52 ± 12.41	465.6 ± 35.83
b	NS	NS	NS	NS
c	P = 0.0001	P = 0.0001	P = 0.0001	P = 0.001
BA	238.91 ± 23.48	199.3 ± 4.93	281.78 ± 19.89	441.8 ± 52.42
a	P = 0.0001	NS	NS	NS
b	P = 0.0001	NS	NS	NS
c	P = 0.0001	P = 0.0001	P = 0.0001	P = 0.004
IR	175.03 ± 45.50	202.4 ± 4.48	293.93 ± 15.70	416.8 ± 19.32
a	NS	NS	NS	NS
c	P = 0.0001	P = 0.0001	P = 0.0001	P = 0.029
BA +IR	177.31 ± 27.77	209.5 ± 8.23	286.04 ± 20.82	458.1 ± 27.81
a	NS	NS	NS	NS
b	NS	NS	NS	NS
c	P = 0.0001	P = 0.0001	P = 0.0001	P = 0.001
BL	117.07 ± 10.01	169.9 ± 1.71	175.89 ± 26.47	353.9 ± 40.76
a	P = 0.0001	P = 0.0001	P = 0.0001	P = 0.001
b	P = 0.0001	P = 0.0001	P = 0.0001	P = 0.029
BA + BL	187.17 ± 13.54	191.9 ± 1.29	195.26 ± 18.53	391.9 ± 21.37
a	NS	P = 0.001	P = 0.0001	P = 0.012
b	NS	P = 0.012	P = 0.0001	NS
c	P = 0.0001	P = 0.0001	NS	NS
BL + IR	187.17 ± 13.54	201. 4 ± 4.07	195.26 ± 18.53	437.5 ± 21.18
a	NS	NS	P = 0.0001	NS
b	NS	NS	P = 0.0001	NS
c	P = 0.0001	P = 0.0001	NS	P = 0.006
BA + BL + IR	161.77 ± 15.77	191.0 ± 3.70	280.07 ± 19.41	411.3 ± 21.01
a	NS	P = 0.001	NS	NS
b	NS	P = 0.007	NS	NS
c	P = 0.002	P = 0.0001	P = 0.0001	P = 0.043

ISSN: 1749-8546