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Table 4 Superoxide dismutase and catalase activity levels in RBCs compacted cells and lung tissue homogenate in rat after different treatment conditions

From: Boswellic acids extract attenuates pulmonary fibrosis induced by bleomycin and oxidative stress from gamma irradiation in rats

Parameters Groups

SOD

Cat

Blood (g/ml packed RBCs)

Lung (μg/g wet tissue)

Blood (μmol/ml packed RBCs

Lung (μmol/g wet tissue)

Control

5.065 ± 0.51

7.366 ± 0.60

398.425 ± 40.57

165.183 ± 18.10

b

NS

NS

NS

NS

c

P = 0.0001

P = 0.01

NS

p = 0.009

BA

5.356 ± 0.47

7.307 ± 1.06

389.510 ± 36.72

162.477 ± 11.25

a

NS

NS

NS

NS

b

NS

NS

NS

NS

c

P = 0.0001

P = 0.014

NS

P = 0.018

IR

4.872 ± 0.53

7.233 ± 0.43

377.941 ± 51.08

166.333 ± 13.41

a

NS

NS

NS

NS

c

P = 0.0001

P = 0.019

NS

P = 0.007

BA +IR

4.875 ± 0.50

6.850 ± 0.84

404.467 ± 12.32

154.373 ± 10.08

a

NS

NS

NS

NS

b

NS

NS

NS

NS

c

P = 0.0001

NS

NS

NS

BL

3.064 ± 0.28

5.973 ± 0.28

382.335 ± 56.22

141.187 ± 1.31

a

P = 0.0001

P = 0.01

NS

p = 0.009

b

P = 0.0001

P = 0.019

NS

P = 0.007

BA + BL

4.805 ± 0.56

7.097 ± 0.29

434.126 ± 45.83

171.960 ± 4.12

a

NS

NS

NS

NS

b

NS

NS

p = 0.026

NS

c

P = 0.0001

P = 0.033

p = 0.039

P = 0.002

BL + IR

4.805 ± 0.56

6.970 ± 0.21

434.126 ± 45.83

157.110 ± 4.84

a

NS

NS

NS

NS

b

NS

NS

p = 0.026

NS

c

P = 0.0001

NS

p = 0.039

NS

BA + BL + IR

4.342 ± 0.77

6.757 ± 0.47

448.533 ± 32.19

181.187 ± 2.17

a

P = 0.025

NS

p = 0.046

NS

b

NS

NS

p = 0.006

NS

c

P = 0.0001

NS

p = 0.009

P = 0.0001

  1. Each value represents mean ± SD (n = 10).
  2. n = Number of tests
  3. a: Significant difference from Control
  4. b: Significant difference from Irradiation group (IR)
  5. c: Significant difference from Bleomycin group (BL)
  6. NS: no significance
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Chinese Medicine

ISSN: 1749-8546

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