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Table 2 Serum biochemical parameters

From: Hepatoprotective effect of ethanolic extract of Trichosanthes lobata on paracetamol-induced liver toxicity in rats

     Parameter Groups (n = 6 for each group)
Control (Group I) Paracetamol Paracetamol + Ethanolic Extract of Trichosanthes lobata
2 g/kg body weight (Group II) silymarin 100 mg/kg body weight (Group III) 200 mg/kg body weight (Group IV) 400 mg/kg body weight (Group V)
     AST (U/l) 37.67 (3.803) 127.3 (25.51)a 30.83 (7.705)a 32.00 (6.899)a 18.50 (9.182)a
     ALT (U/l) 21.67 (1.966) 146.3 (32.38)a 68.17 (22.44)a 64.00 (9.011)b 37.50 (6.686)ns
     ALP (U/l) 187.2 (20.23) 312.0 (62.24)a 204.5 (55.56)a 210.7 (30.75)b 171.80 (19.16)a
Bilurubin (mg/dl) 0.63 (0.2160) 1.10 (0.2191)b 0.40 (0.2608)a 0.35 (0.1871)a 0.23 (0.1033)a
Total protein (g/dl) 1.80 (0.4011) 2.03(0.0811)ns 1.83 (0.3084)ns 1.77 (0.3830)ns 2.11 (0.3147)ns
  1. a, P < 0.001; b, P < 0.01; ns : non significant.
  2. Values are expressed as mean (standard deviation; SD). Statistical significance was calculated with ANOVA followed by Dunnett test comparing treated group with paracetamol group.