Table 3 Differentially expressed peptides in the serum profiles of MG patients before and after QJF treatment
Protein name | Peptide mass | Sequence | Patient (P) vs. healthy control(C) | After (A) vs. Before (B) treatment | ||||
|---|---|---|---|---|---|---|---|---|
Change | P value | Fold change (C/P) | Change | P value | Fold change (B/A) | |||
Complement C3f | 1777.922 | SKITHRIHWESASLL | Down | 0.000 | 1.808 | - | - | - |
1865.019 | SSKITHRIHWESASLL | Down | 0.000 | 2.311 | Up | 0.004 | 0.582 | |
1934.125 | SKITHRIHWESASLLR | Down | 0.043 | 1.412 | - | - | - | |
2021.128 | SSKITHRIHWESASLLR | Down | 0.000 | 2.488 | Up | 0.001 | 0.364 | |
1211.668 | RIHWESASLL | - | - | - | Up | 0.043 | 0.753 | |
Component C4b | 1625.975 | NGFKSHALQLNNRQ | Down | 0.010 | 5.421 | - | - | - |
1739.931 | NGFKSHALQLNNRQI | Down | 0.013 | 2.295 | Down | 0.043 | 1.567 | |
Kallidin II | 904.682 | RPPGFSPF | Down | 0.003 | 1.442 | Down | 0.000 | 3.698 |
α-fibrinogen precursor | 905.452 | FLAEGGGVR | Down | 0.020 | 2.625 | - | - | - |
1020.516 | DFLAEGGGVR | Down | 0.001 | 3.435 | Up | 0.000 | 0.381 | |
1077.550 | GDFLAEGGGVR | Down | 0.001 | 2.156 | - | - | - | |
1206.605 | EGDFLAEGGGVR | Down | 0.023 | 4.059 | - | - | - | |
1350.655 | SGEGDFLAEGGGVR | Down | 0.019 | 2.284 | - | - | - | |
1465.701 | DSGEGDFLAEGGGVR | Down | 0.041 | 3.008 | - | - | - | |
2931.280 | SSSYSKQFTSSTSYNRGDSTFESKSY | Down | 0.006 | 2.025 | - | - | - | |
2553.160 | SSSYSKQFTSSTSYNRGDSTFES | - | - | - | Down | 0.005 | 1.409 | |
Fibrinoligase | 2602.337 | AVPPNNSNAAEDDLPTVELQGVVPR | Down | 0.043 | 1.824 | - | - | - |
Prothrombin | 1389.686 | TSEYQTFFNPR | Down | 0.044 | 1.675 | - | - | - |