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Table 3 Differentially expressed peptides in the serum profiles of MG patients before and after QJF treatment

From: Serum proteomic, peptidomic and metabolomic profiles in myasthenia gravis patients during treatment with Qiangji Jianli Fang

Protein name Peptide mass Sequence Patient (P) vs. healthy control(C) After (A) vs. Before (B) treatment
Change P value Fold change (C/P) Change P value Fold change (B/A)
Complement C3f 1777.922 SKITHRIHWESASLL Down 0.000 1.808 - - -
1865.019 SSKITHRIHWESASLL Down 0.000 2.311 Up 0.004 0.582
1934.125 SKITHRIHWESASLLR Down 0.043 1.412 - - -
2021.128 SSKITHRIHWESASLLR Down 0.000 2.488 Up 0.001 0.364
1211.668 RIHWESASLL - - - Up 0.043 0.753
Component C4b 1625.975 NGFKSHALQLNNRQ Down 0.010 5.421 - - -
1739.931 NGFKSHALQLNNRQI Down 0.013 2.295 Down 0.043 1.567
Kallidin II 904.682 RPPGFSPF Down 0.003 1.442 Down 0.000 3.698
α-fibrinogen precursor 905.452 FLAEGGGVR Down 0.020 2.625 - - -
1020.516 DFLAEGGGVR Down 0.001 3.435 Up 0.000 0.381
1077.550 GDFLAEGGGVR Down 0.001 2.156 - - -
1206.605 EGDFLAEGGGVR Down 0.023 4.059 - - -
1350.655 SGEGDFLAEGGGVR Down 0.019 2.284 - - -
1465.701 DSGEGDFLAEGGGVR Down 0.041 3.008 - - -
2931.280 SSSYSKQFTSSTSYNRGDSTFESKSY Down 0.006 2.025 - - -
2553.160 SSSYSKQFTSSTSYNRGDSTFES - - - Down 0.005 1.409
Fibrinoligase 2602.337 AVPPNNSNAAEDDLPTVELQGVVPR Down 0.043 1.824 - - -
Prothrombin 1389.686 TSEYQTFFNPR Down 0.044 1.675 - - -
  1. Note: “-”indicates that the peptide showed no differential expression.