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Table 1 The effect of apigenin on the frequency of chromosomal aberrations

From: Time course changes of anti- and pro-apoptotic proteins in apigenin-induced genotoxicity

 

No. cells scored

% of aberrant cells (± SD)

Chromosomal aberrations/cell

   

chtg

chtb/f

chrg

chrb/f

r

d

Untreated control

300

55.8 ± 14.27

0.16 ± 0.03

0.51 ± 0.15

0.10 ± 0.07

0.20 ± 0.15

0.035 ± 0.03

0.010 ± 0.01

Vehicle control

300

60.5 ± 5.05

0.15 ± 0.09

0.63 ± 0.19

0.05 ± 0.03

0.32 ± 0.06

0.003 ± 0.01

0.003 ± 0.01

AP (1 μM)

303

56.2 ± 12.57

0.08 ± 0.01

0.49 ± 0.09

0.05 ± 0.03

0.27 ± 0.18

0.013 ± 0.02

0.003 ± 0.01

ΑP (10 μΜ)

300

68.2 ± 13.88

0.13 ± 0.07

0.63 ± 0.12

0.06 ± 0.02

0.33 ± 0.16

0.022 ± 0.03

0.000 ± 0.00

AP (20 μΜ)

300

66.0 ± 6.60

0.16 ± 0.06

0.56 ± 0.05

0.07 ± 0.03

0.41 ± 0.03

0.024 ± 0.02

0.010 ± 0.01

  1. chtg: chromatid gap; chtb: chromatid break; f: fragment; chrg: chromosome gap; chrb: chromosome break; r: ring; d: dicentric.