Cratoxylum formosum (Jack) Dyer ssp. pruniflorum (Kurz) Gogel. (Hóng yá mù) extract induces apoptosis in human hepatocellular carcinoma HepG2 cells through caspase-dependent pathways

Table 1 Cytotoxicity and selectivity index of 50% ethanol-water extract of CF on HepG2 cells compared with Vero cells

Sample	Part used	IC₅₀ ± SD (μg/mL)		Selectivity index (SI)^c
Sample	Part used	HepG2	Vero
Cratoxylum formosum (Jack) Dyer ssp. pruniflorum (Kurz) Gogel.	Twig	55.9 ± 10.6	Inactive^b	8.9
Melphalan^a		37.7 ± 9.8	59.9 ± 3.2	1.6

Data expressed as the mean ± SD of three determinations.
^aStandard anticancer drug.
^bIC₅₀ > 500 μg/mL is considered inactive.
^cSI referred to Selectivity Index, when SI value > 3 indicates high selectivity.

ISSN: 1749-8546