Figure 2

Effects of drugs on liver morphology, weight and biochemical markers after the CCl ₄ injury. All rats were arbitrarily divided into five groups (n = 10): normal group (Nor), model group (Mod), bufothionine group (9.77 mL/kg) (BufoA), glycyrrhizin group (Gly) and cinobufacini injection group (3.42 mL/kg) (InjA). They were treated once daily at a fixed time for 8 d. On the 8th day CCl₄ (1.5 mL/kg) was administered to induce acute liver injury except in the normal group (A: normal rat liver B: rat liver model induced by CCl₄ ). Then they fasted with free access to water. On the 9th day, all rats in each group were anaesthetized to collect blood. Weights data during whole experiment were recorded (C). Liver weight indice was calculated as the ratio of liver weight to weight (D). Serum levels of ALT (E), AST (F), ALP (G) and TBIL (H) were determined. AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase; TBIL: total bilirubin. All data were represented mean ± SD (n = 10).