Skip to main content

Table 1 Compounds in EXD satisfying LR, OB ≥30% and DL ≥0.18

From: Network pharmacological identification of active compounds and potential actions of Erxian decoction in alleviating menopause-related symptoms

  Herbs
HE RC RMO RAS CPC RA
Number of compounds 150 104 189 173 63 81
Compounds (percentage) passing LR 75 (50.0%) 29 (27.9%) 125 (66.1%) 131 (75.7%) 43 (68.3%) 45 (55.6%)
Compounds (percentage) with OB ≥30% and DL ≥0.18 23 (15.3%) 7 (6.7%) 20 (10.6%) 5 (2.9%) 28 (44.4%) 15 (18.5%)
Compounds (percentage) satisfying LR, OB ≥30% and DL ≥0.18 17 (11.3%) 4 (3.8%) 12 (6.3%) 3 (1.7%) 19 (30.2%) 11 (13.6%)
  1. LR Lipinski’s rule, OB oral bioavailability, DL drug-likeness index, HE Herba Epimedium Brevicornum, RC Rhizoma Curculiginis Orchioides, RMO Radix Morindae Officinalis, RAS Radix Angelicae Sinensis, CPC Cortex Phellodendri Chinensis, RA Rhizoma Anemarrhenae asphodeloides.