Parameter
|
Control
|
HFD
|
HFD + Simvastatin
|
HFD + CTS-100
|
HFD + CTS-200
|
---|
Initial body weight (g)
|
21.10 ± 1.62
|
21.22 ± 1.21
|
20.31 ± 1.03
|
21.56 ± 2.02
|
21.64 ± 1.36
|
Final body weight (g)
|
30.35 ± 3.06
|
40.39 ± 3.02##
|
35.63 ± 4.63△
|
37.97 ± 4.13*
|
37.68 ± 2.91*
|
Body weight gain (g)
|
9.25 ± 0.91
|
19.17 ± 0.32#
|
15.32 ± 0.53△
|
16.41 ± 0.44*
|
14.89 ± 0.46*
|
Adipose tissuea weight (g)
|
0.96 ± 0.23
|
1.67 ± 0.49##
|
1.24 ± 0.29△
|
1.37 ± 0.64
|
1.43 ± 0.54*
|
Ratio of adipose tissue and body weight (%)
|
3.22 ± 0.90
|
4.29 ± 1.55##
|
3.51 ± 1.49△
|
3.67 ± 2.16
|
3.84 ± 1.46*
|
Liver weight (g)
|
1.45 ± 0.14
|
2.26 ± 0.17##
|
2.02 ± 0.39△△
|
2.15 ± 0.22
|
2.09 ± 0.39**
|
Ratio of liver and body weight (%)
|
4.81 ± 0.60
|
5.74 ± 0.71##
|
5.50 ± 1.47△
|
5.70 ± 0.70
|
5.63 ± 1.30*
|
- Adipose tissuea: including omental adipose tissue, perirenal adipose tissue, and epididymal adipose tissue.
- Values were expressed as the mean ± SD (n = 10). #
P < 0.05, ##
P < 0.01, HFD vs. control. △
P < 0.05, △△
P < 0.01, HFD vs. simvastatin treatment. *P < 0.05, **P < 0.01, HFD vs. CTS treatment.