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Table 6 Effects of CTS on plasma ALT and AST activities in mice fed with HFD

From: Crude triterpenoid saponins from Ilex latifolia (Da Ye Dong Qing) ameliorate lipid accumulation by inhibiting SREBP expression via activation of AMPK in a non-alcoholic fatty liver disease model

Parameter

Control

HFD

HFD + Simvastatin

HFD + CTS-100

HFD + CTS-200

ALT (KAIU/L)

43.15 Â± 3.98

62.61 Â± 14.81##

51.34 Â± 15.81△△

50.94 Â± 15.95**

40.74 Â± 7.90**

AST (KAIU/L)

104.85 Â± 26.20

101.74 Â± 22.86

127.65 Â± 11.83△△

96.24 Â± 10.18

98.87 Â± 12.61

  1. Values were expressed as the mean Â± SD (n = 10). # P < 0.05, ## P < 0.01, HFD vs. control. â–³ P < 0.05,△△ P < 0.01, HFD vs. simvastatin treatment. *P < 0.05, **P < 0.01, HFD vs. CTS treatment.
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Chinese Medicine

ISSN: 1749-8546

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