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Table 4 Foldchange and degree of Dif-gene

From: Actions of Huangqi decoction against rat liver fibrosis: a gene expression profiling analysis

Gene

Foldchangea

Degree of pathway-gene network

Degree of gene PPI network

PDGFra

−1.56

9

7

PDGFrb

−1.61

9

7

PDGFb

−1.62

8

17

PDGFd

−1.92

6

4

COL1A1

−1.77

2

24

COL1A2

−1.54

2

20

COL5A2

−1.52

2

18

ITGA5

+1.77

7

 

THBS1

−2.22

3

 

IL1R1

+1.58

3

 
  1. aFold change referred to an average ratio for only these cases (frequency) in which the ratio of change (HQD-treated/DMN-treated) was over 1.5-fold. +, up-regulation; −, down-regulation, P < 0.05