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Fig. 3 | Chinese Medicine

Fig. 3

From: Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation in human breast carcinoma MCF-7 cells

Fig. 3

Growth inhibitory activity of ADHC-AXpn in MCF-7 cells. a Cells were treated with increasing concentrations of ADHC-AXpn (10 to 50 μM) for 24 and 48 h; cell survival was then assessed by MTT assay. Doxorubicin (Dox) exposure at 5 μM was used as a positive control. b After exposure to ADHC-AXpn at concentrations of 20, 30 or 35 μM, cells were seeded onto 6-well plates (600 cells/well) for assessing colony formation. Data are expressed as mean ± SD of three independent experiments with **P = 0.0078; ***P < 0.001

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Chinese Medicine

ISSN: 1749-8546

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