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Table 2 Comparison between latent variables and existing CM syndromes

From: Identification of Chinese medicine syndromes in persistent insomnia associated with major depressive disorder: a latent tree analysis

Latent variablesa    CM syndromes
1 2 3 4 5 6 7 8 9 10
Y18 Y18 = s0 Y18 = s1           
  0.43 0.57           
Thirst 0.07 1 ●          
Favour of drinking 0.18 0.78 ●          
Y17 Y17 = s0 Y17 = s1           
  0.34 0.66           
Dry mouth 0.39 1    ● ●    ●   ●  
Dry throat 0.01 0.53    ● ●    ●   ●  
Bitter taste 0.19 0.64 ● ● ●     ●    
Agitation 0.33 0.66     ●       
Y16 Y16 = s0 Y16 = s1           
  0.62 0.38           
Weary limbs 0.31 1       ●     
Sore knees 0.21 0.83     ●    ●   ●  
Hypochondriac pain 0.01 0.29 ●   ●        
Backache 0.51 0.88    ● ●    ●   ●  
Pain in the chest and hypochondrium 0 0.15 ●          
Aphthous stomatitis 0.2 0.53    ●       ●  
Y15 Y15 = s0 Y15 = s1           
  0.81 0.19           
Heavy headedness 0.18 0.88   ●         
Head distension 0.25 0.91 ●          
Difficulty falling asleep alone 0.02 0.25         ●   
Y14 Y14 = s0 Y14 = s1           
  0.69 0.31           
Insomnia with vexation 0.05 0.64     ●    ●   ●  
Restless sleep 0.48 0.93   ●   ●      ●  
Vexation in sitting and lying down 0 0.21         ●   
Difficulty staying asleep 0.79 1     ●    ● ● ●  
Y13 Y13 = s0 Y13 = s1           
  0.82 0.18           
Sleeping late at night 0.29 1    ● ●      ●  
Frequent awakening with a start 0.14 0.75         ●   ●
Half asleep 0.35 0.94       ●     
Poor memory 0.93 0.66    ●    ● ●   ●  
Y12 Y12 = s0 Y12 = s1           
  0.48 0.52           
Headache 0.25 0.82 ● ● ●        
Excessive dreaming 0.38 0.91 ●   ●    ● ● ● ● ●
Night sweating 0.06 0.55    ● ●      ●  
Feverish sensations in the palms soles and chest 0.02 0.43    ● ●    ●   ●  
Tinnitus 0.18 0.54 ●   ● ●    ●   ●  
Y11 Y11 = s0 Y11 = s1           
  0.88 0.12           
Nausea 0.01 1   ●         
Poor appetite 0.16 0.82 ● ●   ●   ● ●    
Y10 Y10 = s0 Y10 = s1           
  0.61 0.39           
Fright palpitation 0.03 0.41          ●  
Dyspnea 0.15 0.58         ●   ●
Tasteless 0.01 0.27       ●     
Lassitude 0.78 1      ●      
Oppression in the chest 0.18 0.53 ● ●   ●       ●
Cold extremities 0.23 0.59          ●  
Y09 Y09 = s0 Y09 = s1           
  0.46 0.54           
Frequent sighing 0.09 0.73 ●          
Fatigue 0.27 0.81 ●   ●        
Vexation 0.14 0.64 ● ● ● ●    ● ● ●  
Unrefreshing sleep 0.72 0.99     ●       
Dizziness 0.09 0.46 ● ● ● ●   ● ●   ●  
Difficulty falling asleep with vexation 0.23 0.63     ●      ●  
Palpitation 0.06 0.34    ●    ● ● ● ● ●
Y08 Y08 = s0 Y08 = s1           
  0.39 0.61           
Thoughtful 0.34 1         ●   
Y07 Y07 = s0 Y07 = s1           
  0.39 0.61           
Impatience 0.09 0.92 ●   ●       ●  
Irritability 0 0.71 ●   ●       ●  
Y05 Y05 = s0 Y05 = s1           
  0.55 0.45           
Belching 0.25 0.96   ●   ● ●      
Gastric stuffiness 0.03 0.42   ●   ●       ●
Stuffiness and pain in stomach and abdomen 0.06 0.38     ●       
Stuffiness in stomach and abdomen 0.13 0.48     ●       
Profuse sputum 0.12 0.43   ●         
Difficulty falling asleep 0.68 0.93 ●   ● ●   ● ● ● ●  
Hypochondriac distension 0.02 0.17 ●          
Y04 Y04 = s0 Y04 = s1           
  0.76 0.24           
Acid regurgitation 0.15 1   ●      ●    
Insomnia 0.56 1   ●      ●    
  1. CM syndrome 1–10 refers to Liver-qi stagnation transforming into fire, Internal disturbance of phlegm-heat, Liver fire flaming upward, Stomach disharmony, Stomach qi disharmony, Deficiency of both the heart and spleen, Hyperactivity of fire due to yin deficiency, Qi deficiency of the heart and gallbladder, Heart-kidney noninteraction, and Heart deficiency with timidity, respectively. The dots represent that the clinical features are often present in the CM syndromes
  2. aThe latent variables are presented starting from the bottom of the latent tree model
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Chinese Medicine

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