Skip to main content

Advertisement

Table 1 Antiproliferative activity of different jujube seed extracts on non-cancer Vero cell line and T cell leukemic Jurkat cell line evaluated by the NR assay for 24 h incubation

From: Apoptosis-inducing effects of jujube (Zǎo) seed extracts on human Jurkat leukemia T cells

Sample IC50 (µg/mL) Selectivity index
Vero cell line Jurkat cell line
Water Ethanol Dichloro-methane Ethyl acetate Chloroform Hexane Water Ethanol Dichloro- methane Ethyl acetate Chloroform Hexane
‘Samros’ Inactive Inactive Inactive nd nd nd Inactive 417.7 ± 10.4b Inactive nd nd nd 1.0
‘Bombay’ Inactive Inactive Inactive Inactive Inactive Inactive Inactive 487.9 ± 17.5a Inactive Inactive Inactive Inactive 1.0
‘Apple’ Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive nd
‘Taiwan’ Inactive Inactive Inactive Inactive nd inactive Inactive 232.4 ± 7.8d Inactive Inactive nd Inactive 2.1
‘Nomsod’ Inactive Inactive Inactive Inactive nd Inactive Inactive 333.4 ± 2.8c Inactive Inactive nd Inactive 1.0
‘Jumbo’ Inactive Inactive Inactive Inactive nd Inactive Inactive 312.0 ± 18.3c Inactive Inactive nd Inactive 1.6
‘Kaew’ Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive nd
‘Rianthong’ Inactive Inactive Inactive Inactive nd Inactive Inactive 401.6 ± 9.9b Inactive Inactive nd Inactive 1.2
Melphalan 75.0 ± 2.3 119.1 ± 10.4e 0.6
  1. Data presented as IC50 values and selectivity index in Jurkat cell line (n = 3)
  2. Means in the same column with different superscript letter(s) are significantly different, P < 0.05 (one-way ANOVA). Inactive means at the extract caused <50 % cytotoxicity even using the maximum concentration at 500 µg/mL
  3. nd not determined due to their low yield