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Table 2 The topmost frequent words for 20 topics after fitting to the ginseng-related articles by Bio-DTM

From: Revealing topics and their evolution in biomedical literature using Bio-DTM: a case study of ginseng

Topic ID

Topmost frequent words of topic

1

Renal, genom, amino, biosynthesi, clone, cultivar, yeast, cdna, athlet, polymorph

2

Stem, skin, leaf, bone, dri, phenol, marrow, stage, fibroblast, wound

3

Infect, radic, scaveng, heat, virus, substrat, cyp3a4, influenza, hydroxyl, pgp

4

Diet, muscl, cholesterol, fat, glycosid, adipocyt, ppargamma, antibodi, ampk, insulin

5

Fraction, polysaccharid, ferment, pesticid, residu, column, frg, transit, neutral, pectin

6

Strain, soil, genus, nov, warfarin, polar, bacterium, minor, dsm, genom

7

Cam, tcm, irradi, hair, radiat, sperm, exhaust, alkalin, train, contamin

8

Channel, ca2, cardiac, relax, oocyt, contract, muscl, eno, lpa, ion

9

Injuri, women, fatigu, myocardi, estrogen, ischemia, menopaus, syndrom, cerebr, ischem

10

Pharmacokinet, ion, formula, prescript, ppd, rhizom, ppt, urin, raw, excret

11

Cultiv, temperatur, wild, seed, white, embryo, genet, flower, somat, pathogen

12

Cancer, lung, colon, intak, metastasi, colorect, ventricular, pulmonari, failur, mmp9

13

Diabet, intestin, insulin, toler, digoxin, absorpt, pancreat, beta, grg1, morphin

14

Apoptosi, macrophag, nfkappab, ros, cox2, cancer, mitochondri, angiogenesi, arrest, p38

15

Transform, medium, hairi, transgen, cold, degrad, spectroscopi, biomass, ml1, callus

16

Breast, vaccin, adjuv, discrimin, prostat, skin, fingerprint, antibodi, metabolom, antigen

17

Pressur, hepat, oil, ethanol, metal, aqueous, allerg, hepatotox, fibrosi, asthma

18

Platelet, lymphocyt, spleen, aggreg, pain, cisplatin, nrf2, antiplatelet, milk, camp

19

Berri, behavior, alcohol, depress, memori, swim, ach, learn, avoid, erectil

20

Neuron, cognit, memori, hippocampus, drink, behavior, glutam, energi, astrocyt, task