Skip to main content

Table 8 Absorption parameters of tripterine in perfusate solution within duodenum, jejunum, ileum and colon (\( {\bar{\text{x}}} \pm {\text{s}} \), n = 6)

From: Different modulation of Panax notoginseng on the absorption profiling of triptolide and tripterine from Tripterygium wilfordii in rat intestine

Parameters Con. (μg/mL) Duodenum Jejunum Ileum Colon
Peff × 10−3 3 7.11 ± 3.68 8.72 ± 3.47 9.48 ± 2.91 10.3 ± 1.56
6 6.93 ± 3.01 9.52 ± 3.28 8.15 ± 3.82 10.8 ± 1.79
9 9.03 ± 1.35 10.5 ± 1.67 9.13 ± 2.63 8.57 ± 3.75
10 cm%ABS 3 4.76 ± 1.27 4.98 ± 2.46 5.62 ± 1.81 6.34 ± 1.63
6 4.69 ± 1.46 5.19 ± 1.44 5.34 ± 2.57 5.59 ± 2.34
9 4.75 ± 0.98 5.09 ± 1.45 5.46 ± 2.24 5.75 ± 1.86
Ka × 10−2 3 1.52 ± 0.41 2.08 ± 0.33 2.62 ± 0.17 1.27 ± 0.19
6 1.66 ± 0.23 2.12 ± 0.23 2.48 ± 0.45 1.03 ± 0.37
9 1.44 ± 0.58 2.03 ± 0.45 2.43 ± 0.74 1.19 ± 0.24