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Table 9 Absorption parameters of tripterine of various formulae in perfusate solution within duodenum, jejunum, ileum and colon (\( {\bar{\text{x}}} \pm {\text{s}} \), n = 6)

From: Different modulation of Panax notoginseng on the absorption profiling of triptolide and tripterine from Tripterygium wilfordii in rat intestine

Parameters Con. (μg/mL) Duodenum Jejunum Ileum Colon
Peff × 10−3 Tripterine 6.78 ± 3.68 8.72 ± 3.47 9.48 ± 2.91 10.3 ± 1.56
TW 7.11 ± 2.77 10.7 ± 4.51 11.6 ± 3.01 12.4 ± 3.63
TW-PN 10.3 ± 1.14* 13.3 ± 4.08 15.2 ± 2.63 9.98 ± 0.21
TW-CS 3.20 ± 0.49** 3.35 ± 0.78** 5.69 ± 2.12** 3.39 ± 1.15**
QLTB 11.7 ± 0.82** 11.1 ± 5.3 6.10 ± 3.63* 5.62 ± 3.11**
10 cm%ABS Tripterine 4.76 ± 1.27 4.98 ± 2.46 5.62 ± 1.81 6.34 ± 1.63
TW 5.87 ± 1.23 6.27 ± 2.26 7.60 ± 1.17# 7.14 ± 1.63
TW-PN 6.49 ± 1.91 9.29 ± 0.54** 9.43 ± 0.56** 5.82 ± 1.42
TW-CS 2.91 ± 0.49** 3.74 ± 0.95* 4.23 ± 2.67* 3.97 ± 1.19**
QLTB 8.13 ± 0.81** 7.38 ± 1.07 4.84 ± 1.58** 5.65 ± 1.31
Ka × 10−2 Tripterine 1.52 ± 0.41 2.08 ± 0.33 2.62 ± 0.17 1.27 ± 0.19
TW 1.88 ± 0.38 2.21 ± 0.51 2.91 ± 0.35 1.34 ± 0.54
TW-PN 2.31 ± 0.83 3.27 ± 0.21** 3.21 ± 0.14 2.52 ± 0.13**
TW-CS 1.64 ± 0.30 1.22 ± 0.20** 1.39 ± 0.40** 1.54 ± 0.11
QLTB 2.14 ± 0.30 1.69 ± 0.45 1.86 ± 0.16** 1.66 ± 0.31
  1. #p < 0.05, compared with tripterine; * p < 0.05, ** p < 0.01, compared with TW