Fig. 8

Combined effects of furanodiene (FUR) and doxorubicin (DOX) on viability of DOX-resistant MCF-7 cells. a Cells were treated with different concentrations of furanodiene (FUR; 0–100 µM) in the presence or absence of doxorubicin (DOX; 2 µM) for 24 h. b Cells were treated with different concentrations of DOX (0–100 µM) in the presence or absence of FUR (25 µM) for 24 h. Cell viability was assessed using MTT assay. c The results were analyzed using CalcuSyn program (Biosoft), based on Chou–Talalay method. Data shown were expressed as mean ± S.E.M. ns stands for not significant. *, synergism