Fig. 1

a, b Effect of SKN, PTX or their combinations on cell viability of human ovarian cancer cells. A2780 (a) and A2780/PTX (b) cells were seeded in 96-well plates at a density of 3000/well and treated with SKN (0, 1, 2 μM), PTX (0, 1, 10, 100, 1000 nM), or SKN/PTX combinations for 24 h, followed by SRB assay. c, d Combination index (CI) was calculated using CompuSyn Software. Data generated from A2780 (c) or A2780/PTX (d) cells were used. CI < 1, synergistic effect; CI = 1, additive effect; CI > 1, antagonistic effect