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Table 2 Up-regulated proteins with a fold change > 2.0 under GZZSZTW treatment (GZZSZTW vs. Blank)

From: Dissection of the molecular targets and signaling pathways of Guzhi Zengsheng Zhitongwan based on the analysis of serum proteomics

Protein name Fold change p value
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (DHX15) 7.11 0.01
Protein GREB1 (GREB1) 4.68 0.02
AF4/FMR2 family member 3 (AFF3) 3.85 0.03
Rootletin (CROCC) 3.55 0.04
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) 3.31 0
Fibrinogen beta chain (FGB) 3.19 0
Chromodomain-helicase-DNA-binding protein 1-like (CHD1L) 3.11 0
Sodium bicarbonate transporter-like protein 11 (SLC4A11) 3.08 0
Fibrinogen gamma chain (FGG) 2.82 0
Calmodulin-regulated spectrin-associated protein 1 (CAMSAP1) 2.71 0
Four and a half LIM domains protein 1 (FHL1) 2.68 0
MOB kinase activator 1A (MOB1A) 2.65 0
Tubulin alpha-4A chain (TUBA4A) 2.58 0
Myelin regulatory factor (MYRF) 2.57 0
Von Ebner gland protein 1 (VEGP1) 2.56 0.01
Pro-interleukin-16 (IL16) 2.47 0
Elongation factor 1-beta (EEF1B) 2.45 0.01
Transgelin-2 (TAGLN2) 2.41 0
Destrin (DSTN) 2.40 0
Coronin-1A (CORO1A) 2.40 0
WD repeat-containing protein 1 (WDR1) 2.39 0
Flavin reductase (NADPH) (BLVRB) 2.35 0.01
Inorganic pyrophosphatase (PPA1) 2.35 0.01
Tubulin beta chain (TUBB) 2.35 0
Adenylyl cyclase-associated protein 1 (CAP1) 2.34 0
Disks large-associated protein 4 (DLGAP4) 2.29 0.01
EH domain-containing protein 3 (EHD3) 2.26 0
T-complex protein 1 subunit zeta (CCT6A) 2.25 0
Carboxypeptidase B2 (CPB2) 2.24 0
Beta-parvin (PARVB) 2.23 0
Profilin-1 (PFN1) 2.21 0
Pleckstrin (PLEK) 2.18 0
LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1) 2.17 0
Inverted formin-2 (INF2) 2.16 0.01
Dynein light chain 1, cytoplasmic (DYNLL1) 2.15 0
Protein S100-A4 (S100A4) 2.15 0.02
Cysteine and glycine-rich protein 1 (CSRP1) 2.14 0.04
Filamin-A (FLNA) 2.10 0
Peptidyl-prolyl cis-trans isomerase A (PPIA) 2.10 0
Transitional endoplasmic reticulum ATPase (VCP) 2.10 0
Myosin light chain kinase family member 4 (MYLK4) 2.09 0.02
Calmodulin-2 B (CALM2B) 2.07 0
Alpha-actinin-1 (ACTN1) 2.07 0
Microtubule-associated protein RP/EB family member 2 (MAPRE2) 2.07 0
GMP reductase 1 (GMPR) 2.04 0.01
Aspartate-tRNA ligase, cytoplasmic (DARS) 2.03 0.03
Cofilin-1 (CFL1) 2.02 0
Hsc70-interacting protein (ST13) 2.01 0