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Table 2 Up-regulated proteins with a fold change > 2.0 under GZZSZTW treatment (GZZSZTW vs. Blank)

From: Dissection of the molecular targets and signaling pathways of Guzhi Zengsheng Zhitongwan based on the analysis of serum proteomics

Protein name

Fold change

p value

Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (DHX15)

7.11

0.01

Protein GREB1 (GREB1)

4.68

0.02

AF4/FMR2 family member 3 (AFF3)

3.85

0.03

Rootletin (CROCC)

3.55

0.04

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

3.31

0

Fibrinogen beta chain (FGB)

3.19

0

Chromodomain-helicase-DNA-binding protein 1-like (CHD1L)

3.11

0

Sodium bicarbonate transporter-like protein 11 (SLC4A11)

3.08

0

Fibrinogen gamma chain (FGG)

2.82

0

Calmodulin-regulated spectrin-associated protein 1 (CAMSAP1)

2.71

0

Four and a half LIM domains protein 1 (FHL1)

2.68

0

MOB kinase activator 1A (MOB1A)

2.65

0

Tubulin alpha-4A chain (TUBA4A)

2.58

0

Myelin regulatory factor (MYRF)

2.57

0

Von Ebner gland protein 1 (VEGP1)

2.56

0.01

Pro-interleukin-16 (IL16)

2.47

0

Elongation factor 1-beta (EEF1B)

2.45

0.01

Transgelin-2 (TAGLN2)

2.41

0

Destrin (DSTN)

2.40

0

Coronin-1A (CORO1A)

2.40

0

WD repeat-containing protein 1 (WDR1)

2.39

0

Flavin reductase (NADPH) (BLVRB)

2.35

0.01

Inorganic pyrophosphatase (PPA1)

2.35

0.01

Tubulin beta chain (TUBB)

2.35

0

Adenylyl cyclase-associated protein 1 (CAP1)

2.34

0

Disks large-associated protein 4 (DLGAP4)

2.29

0.01

EH domain-containing protein 3 (EHD3)

2.26

0

T-complex protein 1 subunit zeta (CCT6A)

2.25

0

Carboxypeptidase B2 (CPB2)

2.24

0

Beta-parvin (PARVB)

2.23

0

Profilin-1 (PFN1)

2.21

0

Pleckstrin (PLEK)

2.18

0

LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1)

2.17

0

Inverted formin-2 (INF2)

2.16

0.01

Dynein light chain 1, cytoplasmic (DYNLL1)

2.15

0

Protein S100-A4 (S100A4)

2.15

0.02

Cysteine and glycine-rich protein 1 (CSRP1)

2.14

0.04

Filamin-A (FLNA)

2.10

0

Peptidyl-prolyl cis-trans isomerase A (PPIA)

2.10

0

Transitional endoplasmic reticulum ATPase (VCP)

2.10

0

Myosin light chain kinase family member 4 (MYLK4)

2.09

0.02

Calmodulin-2 B (CALM2B)

2.07

0

Alpha-actinin-1 (ACTN1)

2.07

0

Microtubule-associated protein RP/EB family member 2 (MAPRE2)

2.07

0

GMP reductase 1 (GMPR)

2.04

0.01

Aspartate-tRNA ligase, cytoplasmic (DARS)

2.03

0.03

Cofilin-1 (CFL1)

2.02

0

Hsc70-interacting protein (ST13)

2.01

0