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Table 5 Effects of timosaponin BII and timosaponin BIII on the content of 5-HT and DA

From: Identifying the active components of Baihe–Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests

Groups

Dosage (mg/kg)

Content (ng/g)

5-HT

DA

Control

–

636.2 ± 80.1

171.6 ± 54.5

Fluoxetine

10

731.3 ± 104.6*

215.9 ± 36.5*

Timosaponin BII

10

716.5 ± 90.4*

196.9 ± 56.7

Timosaponin BIII

10

705.6 ± 47.7*

191.3 ± 69.8

  1. 5-HT and DA represented serotonin and dopamine, respectively
  2. * P < 0.05 compared with blank group
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Chinese Medicine

ISSN: 1749-8546

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