Fig. 2

Effect of environment on body weight of mice and effects of three TCM compounds on body weight loss and lung index of mice infected with influenza virus. a Changes of body weight in mice for 11 days of environmental modeling. 20 °C, 50RH%-C57BL/6 wild type (b), 33 °C, 90RH%-C57BL/6 wild type (c) and 33 °C, 90RH%- TLR7^−/− (d) mice were infected with 50 μL FM1 virus on day 11 and then were gavaged with distilled water, containing oseltamivir, XJXRY, GZMHGBT or YQS daily 24 h after virus infection, respectively. Changes in body weight of each mouse were recorded. Statistical analysis was performed by one-way ANOVA with repeated measures (a) and one-way ANOVA (b–d). P* = P value for Bonferroni correction. *P < 0.05, **P < 0.01, ***P < 0.001