Fig. 5

Disturbed metabolic pathways in stomach related to GML pathology and moxibustion treatment at three time points. 1, Phenylalanine, tyrosine and tryptophan biosynthesis; 2, d-glutamine and d-glutamate metabolism; 3, valine, leucine and isoleucine biosynthesis; 4, alanine, aspartate and glutamate metabolism; 5, phenylalanine metabolism; 6, glyoxylate and dicarboxylate metabolism; 7, citrate cycle (TCA cycle); 8, pyruvate metabolism; 9, starch and sucrose metabolism; 10, Aminoacyl-tRNA biosynthesis; 11, glycolysis or gluconeogenesis; 12, arginine and proline metabolism; 13, tyrosine metabolism. Metabolites in bold were remarked metabolites associated with moxibustion treatment on GML rats. (Those in red (or blue) indicate concentration increases (or decreases) in comparison with the control group, while ones in black present no insignificant change)