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Table 2 The main pathway affected between PMR and PMRP group

From: Metabolomics profiling of Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparata extracts using UPLC-Q/TOF-MS

Main pathway

Totala

Hitsb

Raw Pc

Holm Pd

−log(P)e

Impactf

alpha-Linolenic acid metabolism

9

2

0.0031

0.2542

5.7640

1.0000

Taurine and hypotaurine metabolism

8

1

0.0765

1

2.5699

0.4286

Glycerophospholipid metabolism

30

2

0.0337

1

3.3909

0.1833

Arginine and proline metabolism

44

1

0.3583

1

1.0263

0.1274

Primary bile acid biosynthesis

46

2

0.0732

1

2.6141

0.0298

  1. aTotal: the total number of compounds in the pathway
  2. bHits: the matched number of metabolites in one pathway
  3. cRaw P: the original P value calculated from the enrichment analysis
  4. dHolm P: the P value further adjusted using Holm-Bonferroni method
  5. e−log(P): Y-axis values
  6. fImpact: the pathway impact value calculated from pathway topology analysis
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Chinese Medicine

ISSN: 1749-8546

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