Table 1 Secondary metabolites of Chaetomium in Ginkgo biloba

1

(22E, 24R)-ergosta-7,22-diene-3β,5α,6β-triol/cerevisterol

516-37-0

Chaetomium globosum

[33]

2

(22E, 24R)-ergosta-7,22-diene-3β,5α,6β,9α-tetraol

88191-06-4

Chaetomium globosum

[44]

3

(7Z,11E)-7,11-Hexadecadien-1-yl acetate

53042-79-8

Chaetomium globosum No. 16

Pesticide

[45]

4

(E,E)-2,4-Decadienal

25152-84-5

Chaetomium globosum No. 16

Food_additive; fragrance

[45]

5

(Z)-9-Hexadecenoic acid, methyl ester

1120-25-8

Chaetomium globosum No. 16

[45]

6

(Z,Z)-9,12-Octadecadienoic acid

60-33-3

Chaetomium globosum No. 16

Biosynthesis of prostaglandins and cell membranes

[45]

7

1-(3-Acetyl-2,2-dimethylcyclopropyl)-2-methyl-1-propanone

77142-84-8

Chaetomium globosum T16

[49]

8

1-(3-Methoxy-2-pyrazinyl)-2-methyl-1-propanone

98618-81-6

Chaetomium globosum T16

[46]

9

1,3-Dioxolane, 2-methoxy

19693-75-5

Chaetomium globosum T16

[46]

10

1-Eicosene

3452-07-1

Chaetomium globosum No. 16

[45]

11

1-Trimethylsilyl methanol

3219-63-4

Chaetomium globosum T16

[46]

12

2,3,4-Trimethyl-5,7-dihydroxy-2,3-dihydrobenzofuran

1824584-79-3

Chaetomium globosum

[47]

13

2,4,5-Trimethyl-1,3-dioxolane

3299-32-9

Chaetomium globosum T16

Flavors

[46]

14

2,4-Decadienal

2363-88-4

Chaetomium globosum No.16

Food additive

[20, 21]

15

2′-O-Methyladenosine

2140-79-6

Chaetomium globosum

Inhibition of vaccinia virus growth

[47]

16

2′-Deoxyadenosine

958-09-8

Chaetomium globosum

Anti-tumor and antiviral nucleoside drugs (cladribine)

[44]

17

20-Dihydrochaetoglobosin A

149560-98-5

Chaetomium globosum

[47]

18

21 Methoxy-Chaetoglobosin F

Chaetomium globosum

[47]

18

2-Cyclohexyl-hex-5-en-2-ol

959261-17-7

Chaetomium globosum T16

[46]

19

2-Ethyl-5-propylphenol

72386-20-0

Chaetomium globosum T16

[46]

20

2-Methyl-5-propyl-2,4-dihydro-3H-pyrazol-3-one

31272-04-5

Chaetomium globosum T16

[46]

21

2-Octyl-cyclopropaneoctanal

56196-06-6

Chaetomium globosum No.16

[45]

22

3,4-Dihydroxyphenyl acetic acid

102-32-9

Chaetomium globosum

A metabolite of dopamine, Cytoplasm, Encephalitis, Hypothyroidism, Alzheimer’s disease, Colorectal cancer

[47]

23

3-Methylorsellinic acid

4707-46-4

Chaetomium globosum ZY-22

Neuroprotective Activity

[46]

24

4-Aminophenylacetic acid/p-aminophenylacetic acid/4-aminophenylacetic acid

1197-55-3

Chaetomium globosum

Anti-inflammatory Inhibition colitis

[47]

25

4-Methyl-1-hepten-5-one

26118-97-8

Chaetomium globosum

[46]

26

5-(hydroxymethyl)-1H-pyrrole-2-carbaldehyde

67350-50-9

Chaetomium globosum

Hapten, produces advanced glycation end-products (AGEs)

[47]

27

5′-Epichaetovirdin A

1308671-17-1

Chaetomium globosum No. 12

[45]

28

5′-Deoxy-5′-methylamino-adenosine

No cas no.

Chaetomium globosum

[47]

29

9(11)-dehyoergosterol peroxide

86363-50-0

Chaetomium globosum ZY-22

[44]

30

9,12-Octadecadien-1-ol

1577-52-2

Chaetomium globosum No. 16

[45]

31

Acetaldehyde, diethyl acetal

105-57-7

Chaetomium globosum T16

Used in fruit, rum and whisky flavour

[46]

32

Adenosine

58-61-7

Chaetomium globosum ZY-22

Vasodilatory, anti-arrhythmic and analgesic activities adenosine is an adenosine receptor agonist

[46]

33

Allantoin

97-59-6

Chaetomium globosum

Healing, soothing, and anti-irritating properties anti-acne products, sun care products, and clarifying lotions 

[48]

34

alpha-Methylstyrene

98-83-9

Chaetomium globosum

Membrane adhesives and sealant chemicals

[48]

35

Anthranilic acid

118-92-3

Chaetomium globosum MX-0510

A water-soluble vitamin

[33]

36

Benzeneacetic acid

103-82-2

Chaetomium globosum No. 16

Used in the manufacture of penicillin and bendazol

[45]

37

Benzeneacetic acid, methyl ester

101-41-7

Chaetomium globosum No. 16

Used in the manufacture of atropine

[45]

38

Benzeneethanol/phenylethyl alcohol

60-12-8

Chaetomium globosum

Essence

[45]

39

Butyraldehyde, 4-phenyl

18328-11-5

Chaetomium globosum T16

[46]

40

Cerebroside B

88642-46-0

Chaetomium globosum ZY-22

[46]

41

Cerebroside C

98677-33-9

Chaetomium globosum ZY-22

[46]

42

Chaetoglobosin A

50335-03-0

Chaetomium globosum

[44, 49]

43

Chaetoglobosin B

50335-04-1

Chaetomium globosum CDW7

[48]

44

Chaetoglobosin C

50645-76-6

Chaetomium globosum

[26, 28]

45

Chaetoglobosin D

55945-73-8

Chaetomium globosum

[49]

46

Chaetoglobosin E

55945-74-9

Chaetomium globosum (CDW7)

[49]

47

Chaetoglobosin F

55945-75-0

Chaetomium globosum (CDW7)

[47]

48

Chaetoglobosin Fa

1599426-06-8

Chaetomium globosum

[47]

49

Chaetoglobosin Fex

149457-95-4

Chaetomium globosum

[47]

50

Chaetoglobosin G

65773-98-0

Chaetomium globosum (NM0066)

[47]

51

Chaetoglobosin R

777939-30-7

Chaetomium globosum

[49]

52

Chaetoglobosin V

1399682-37-1

Chaetomium globosum

[47]

53

Chaetoglobosin Vb

1399690-75-5

Chaetomium globosum (CDW7)

[48]

54

Chaetoglobosin Y

1608108-89-9

Chaetomium globosum

[48]

55

Chaetomugilide A

1418138-71-2

Chaetomium globosum

[45, 47]

56

Chaetomugilide B

1433976-48-7

Chaetomium globosum

[45]

57

Chaetomugilide C

1418138-70-1

Chaetomium globosum

[45, 47]

58

Chaetomugilin A

1041640-66-7

Chaetomium globosum

[45]

59

Chaetomugilin D

1098081-38-9

Chaetomium globosum

[25]

60

Chaetomugilin I

1187848-00-5

Chaetomium globosum

[25]

61

Chaetomugilin J

1187848-01-6

Chaetomium globosum

[25]

62

Chaetomugilin O

1187848-06-1

Chaetomium globosum

[25]

63

Chaetomugilin Q

1319729-85-5

Chaetomium globosum

[25]

64

Chaetomugilin S

1399093-77-6

Chaetomium globosum

[25]

65

Chaetoviridin C

128230-02-4

Chaetomium globosum

[15]

66

Chaetoviridin D

128230-04-6

Chaetomium globosum

[33]

67

Chaetoviridin E

1178875-15-4

Chaetomium globosum

[33]

68

Cyclo-(Phe-Gly)

5037-75-2

Chaetomium globosum

[33]

69

Cyclopentadecane

295-48-7

Chaetomium globosum No.16

[45]

70

Dimethyl phthalate

131-11-3

Chaetomium globosum No.16

Used in plastics, insect repellents, safety glass, and lacquer coatings

[45]

71

Epimwsokorwnone A

1073-96-7

Chaetomium globosum

[33]

72

Ergosta-4 6,8,22-tetraen-3-one/ergosta-4,6,8,22-tetraen-3-one

194721-75-0

Chaetomium globosum (ZY-22)

[33]

73

Ergosterol

57-87-4

Chaetomium globosum

Formation of vitamin D2

[49]

74

Ergosterol peroxide (5α,8α-epi-dioxy-(22E,24R) -ergosta-6,22-dien-3β-ol)

2061-64-5

Chaetomium globosum

An antineoplastic agent, an antimycobacterial drug and a trypanocidal drug

[33]

75

Ethanoic acid

64-19-7

Chaetomium globosum T16

Food additive, and in petroleum production

[46]

76

Ethyl 13-methyl-tetradecanoate

64317-63-1

Chaetomium globosum No. 16

[45]

77

Ethyl 2-heptenoate

2351-88-4

Chaetomium globosum T16

[45]

78

Ethylidene acetate

542-10-9

Chaetomium globosum T16

[45]

79

flavipin (1,2-benzenedicarboxaldehyde-3,4,5-trihydroxy-6-methyl)

483-53-4

Chaetomium globosum CDW7

Antioxidant fungicides

[22]

80

Fumigaclavine B

6879-93-2

Chaetomium globosum

[47]

81

Fumitremorgin C

118974-02-0

Chaetomium globosum (NM0066)

A mycotoxin and a breast cancer resistance protein inhibitor

[33]

82

Gliotoxin

67-99-2

Chaetomium globosum (NM0066)

A mycotoxin, an immunosuppressive agent, an protein farnesyltransferase inhibitor, a proteasome inhibitor and an antifungal agent

[33]

83

Globosterol

1193319-70-8

Chaetomium globosum ZY-22

[44]

84

Glycerol formal

5464-28-8

Chaetomium globosum T16

[46]

85

Hexadecane

544-76-3

Chaetomium globosum

Used as a solvent and an ingredient in gasoline and diesel and jet fuels

[45]

86

Hexadecanoic acid, ethyl ester

628-97-7

Chaetomium globosum No. 16

Used as softener, lubricant, food additive

[45]

87

Hexadecanoic acid, methyl ester

112-39-0

Chaetomium globosum No. 16

Used as intermediate of emulsifier, wetting agent, stabilizer and plasticizer

[45]

88

Indole-3- carboxylic acid

771-50-6

Chaetomium globosum ZY-22

Used for synthesis of to rise tron and antiviral drugs

[33]

89

Indole-3-acetic acid

87-51-4

Chaetomium globosum

Plant growth stimulating hormone

[33]

90

Isopentyl alcohol, acetate

123-92-2

Chaetomium globosum T16

Used as a solvent and preparation of a variety of flavor food flavor

[22]

91

Lactic acid

50-21-5

Chaetomium globosum T16

Used to make some plasticizers, adhesives, pharmaceuticals and salts, used in the leather tanning industry and as a solvent

[46]

92

Lactic acid, 2-methyl-,ethyl ester

80-55-7

Chaetomium globosum T16

[46]

93

Maltol

118-71-8

Chaetomium globosum MX-0510

Food additive

[33]

94

Mannitol

87-78-5

Chaetomium globosum

Used as an osmotic diuretic

[33]

95

Methyl 13-methyltetradecanoate

5129-59-9

Chaetomium globosum No. 16

[45]

96

Methyl 9,12-heptadecadienoate

15620-59-4

Chaetomium globosum No. 16

[45]

97

Methyl vinylcarbinol

598-32-3

Chaetomium globosum

Food additive

[46]

98

Methylthiogliotoxin

74149-38-5

Chaetomium globosum (NM0066)

[33]

99

o-Coumaric acid

583-17-5

Chaetomium globosum ZY-22

An antioxidant and is believed to reduce the risk of stomach cancer by reducing the formation of carcinogenic nitrosamines

[33]

100

Octanoic acid, methyl ester

111-11-5

Chaetomium globosum No. 16

Food additive

[45]

101

Pentadecane

629-62-9

Chaetomium globosum No. 16

Used as a solvent and in some household pesticides

[45]

102

Pentadecanoic acid, methyl ester

7132-64-1

Chaetomium globosum No. 16

Fuels and fuel additives

Intermediates, pesticide

[45]

103

p-Hydroxybenzoic acid

99-96-7

Chaetomium globosum

Used as preservatives, fungicides

[33]

104

Pseurotin A

58523-30-1

Chaetomium globosum (NM0066)

An azaspiro compound, an oxaspiro compound and a lactam

[33]

105

Quercetin

117-39-5

Chaetomium globosum GCZX015

Combined with chemotherapeutic drugs, produces anti-inflammatory and anti-allergy effects

[33]

106

Squalene

111-02-4

Chaetomium globosum (NM0066)

Investigated as an adjunctive cancer therapy, also used as cosmetics and dietary supplement

[33]

107

S-Tetrachloroethane

79-34-5

Chaetomium globosum T16

Used to make paint, varnish and rust removers, as a solvent and as an ingredient in pesticides

[45]

108

Succinic acid

110-15-6

Chaetomium globosum

A radiation protective agent, an anti-ulcer drug

[33]

109

Tetradecane

629-59-4

Chaetomium globosum No.16

Used as a solvent and some pesticide sprays

[45]

110

Thymine

65-71-4

Chaetomium globosum ZY-22

A pyrimidine nucleobase and a pyrimidone

[33]

111

Tridecane

629-50-5

Chaetomium globosum No. 16

Used as a solvent and as an ingredient in gasoline and diesel and jet fuel

[45]

112

Triethylene glycol monomethyl ether acetate

3610-27-3

Chaetomium globosum T16

[46]

113

Uracil

66-22-8

Chaetomium globosum ZY-22

Use in the body to help synthesis of many enzymes, and the biosynthesis of polysaccharides and the transportation of sugars containing aldehydes

[49]

114

α-Guajene

3691-12-1

Chaetomium globosum No. 16

[45]