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Table 2 Profiles of polyunsaturated fatty acids in the cortex from fish oil-treated mice and the control mice with corn oil treatment (n = 3 per group)

From: Fish oil protects the blood–brain barrier integrity in a mouse model of Alzheimer’s disease

Fatty acidCortex
Corn oil-miceFish oil-mice
ω-6 PUFA
 LA (C18:2 ω-6)0.87 ± 0.070.89 ± 0.05
 EDA (C20:2 ω-6)0.29 ± 0.060.26 ± 0.03
 DGLA (C20:3 ω-6)0.57 ± 0.020.53 ± 0.04
 AA (C20:4 ω-6)16.21 ± 0.1813.02 ± 0.65*
 DTA (C22:4 ω-6)4.23 ± 0.223.99 ± 0.15
 n-6 DPA (C22:5 ω-6)4.89 ± 0.451.69 ± 0.25***
 Total27.87 ± 1.3520.76 ± 1.31*
ω-3 PUFA
 ω-3 DPA (C22:5 ω-3)0.14 ± 0.010.39 ± 0.01**
 DHA (C22:6 ω-3)15.82 ± 1.0225.05 ± 1.32**
 Total17.12 ± 0.5827.21 ± 1.28**
Total PUFA34.26 ± 1.4544.26 ± 1.65*
ω-6/ω-31.89 ± 0.070.61 ± 0.09**
  1. Data expressed as mol% of total fatty acids ± SEM (*P < 0.05; **P < 0.01; ***P < 0.001). AA arachidonic acid, DGLA dihomo-γ-linolenic acid, DHA docosahexaenoic acid, DPA docosapentaenoic acid, DTA docosatetraenoic acid, EDA eicosadienoic acid, LA linoleic acid, MUFA monounsaturated fatty acids (the value is given as follows: C16:1 + C18:1 + C20:1 + C22:1), SFA saturated fatty acids(the value is given as follows: C14:0 + C15:0 + C16:0 + C17:0 + C18:0 + C20:0 + C22:0 + C24:0), PUFA polyunsaturated fatty acids