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Table 2 Profiles of polyunsaturated fatty acids in the cortex from fish oil-treated mice and the control mice with corn oil treatment (n = 3 per group)

From: Fish oil protects the blood–brain barrier integrity in a mouse model of Alzheimer’s disease

Fatty acid

Cortex

Corn oil-mice

Fish oil-mice

ω-6 PUFA

 LA (C18:2 ω-6)

0.87 ± 0.07

0.89 ± 0.05

 EDA (C20:2 ω-6)

0.29 ± 0.06

0.26 ± 0.03

 DGLA (C20:3 ω-6)

0.57 ± 0.02

0.53 ± 0.04

 AA (C20:4 ω-6)

16.21 ± 0.18

13.02 ± 0.65*

 DTA (C22:4 ω-6)

4.23 ± 0.22

3.99 ± 0.15

 n-6 DPA (C22:5 ω-6)

4.89 ± 0.45

1.69 ± 0.25***

 Total

27.87 ± 1.35

20.76 ± 1.31*

ω-3 PUFA

 ω-3 DPA (C22:5 ω-3)

0.14 ± 0.01

0.39 ± 0.01**

 DHA (C22:6 ω-3)

15.82 ± 1.02

25.05 ± 1.32**

 Total

17.12 ± 0.58

27.21 ± 1.28**

Total PUFA

34.26 ± 1.45

44.26 ± 1.65*

ω-6/ω-3

1.89 ± 0.07

0.61 ± 0.09**

  1. Data expressed as mol% of total fatty acids ± SEM (*P < 0.05; **P < 0.01; ***P < 0.001). AA arachidonic acid, DGLA dihomo-γ-linolenic acid, DHA docosahexaenoic acid, DPA docosapentaenoic acid, DTA docosatetraenoic acid, EDA eicosadienoic acid, LA linoleic acid, MUFA monounsaturated fatty acids (the value is given as follows: C16:1 + C18:1 + C20:1 + C22:1), SFA saturated fatty acids(the value is given as follows: C14:0 + C15:0 + C16:0 + C17:0 + C18:0 + C20:0 + C22:0 + C24:0), PUFA polyunsaturated fatty acids