From: Fish oil protects the blood–brain barrier integrity in a mouse model of Alzheimer’s disease
Fatty acid | Cortex | |
---|---|---|
Corn oil-mice | Fish oil-mice | |
ω-6 PUFA | ||
LA (C18:2 ω-6) | 0.87 ± 0.07 | 0.89 ± 0.05 |
EDA (C20:2 ω-6) | 0.29 ± 0.06 | 0.26 ± 0.03 |
DGLA (C20:3 ω-6) | 0.57 ± 0.02 | 0.53 ± 0.04 |
AA (C20:4 ω-6) | 16.21 ± 0.18 | 13.02 ± 0.65* |
DTA (C22:4 ω-6) | 4.23 ± 0.22 | 3.99 ± 0.15 |
n-6 DPA (C22:5 ω-6) | 4.89 ± 0.45 | 1.69 ± 0.25*** |
Total | 27.87 ± 1.35 | 20.76 ± 1.31* |
ω-3 PUFA | ||
ω-3 DPA (C22:5 ω-3) | 0.14 ± 0.01 | 0.39 ± 0.01** |
DHA (C22:6 ω-3) | 15.82 ± 1.02 | 25.05 ± 1.32** |
Total | 17.12 ± 0.58 | 27.21 ± 1.28** |
Total PUFA | 34.26 ± 1.45 | 44.26 ± 1.65* |
ω-6/ω-3 | 1.89 ± 0.07 | 0.61 ± 0.09** |